Gal antigen-deficient rabbits with GGTA1 gene disruption via CRISPR/Cas9

Previous studies have identified the carbohydrate epitope Gal[alpha]1-3Gal[beta]1-4GlcNAc-R (termed the [alpha]-galactosyl epitope), known as the [alpha]-Gal antigen as the primary xenoantigen recognized by the human immune system. The [alpha]-Gal antigen is regulated by galactosyltransferase (GGTA1...

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Veröffentlicht in:	BMC genomic data 2022-07, Vol.23 (1)
Hauptverfasser:	Wei, Lina, Mu, Yufeng, Deng, Jichao, Wu, Yong, Qiao, Ying, Zhang, Kun, Wang, Xuewen, Huang, Wenpeng, Shao, Anliang, Chen, Liang, Zhang, Yang, Li, Zhanjun, Lai, Liangxue, Qu, Shuxin, Xu, Liming
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Antigenic determinants Gene expression Genes Genetic aspects Genetic research Immune response Medical equipment Physiological apparatus Risk assessment
Online-Zugang:	Volltext
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