Safety and Long-Term Outcomes of Rotablation in Patients with Reduced
Clinical outcomes in patients with reduced left ventricular systolic function undergoing rotational atherectomy (RA) for percutaneous coronary intervention (PCI) remain understudied. Our study sought to evaluate the impact of RA-PCI in patients with LV systolic dysfunction on long-term outcomes. Bet...
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| Veröffentlicht in: | Journal of clinical medicine 2023-08, Vol.12 (17) |
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| container_issue | 17 |
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| container_title | Journal of clinical medicine |
| container_volume | 12 |
| creator | Ayoub, Mohamed Tajti, Péter Akin, Ibrahim Behnes, Michael Schupp, Tobias Forner, Jan Omran, Hazem Westermann, Dirk Rudolph, Volker Mashayekhi, Kambis |
| description | Clinical outcomes in patients with reduced left ventricular systolic function undergoing rotational atherectomy (RA) for percutaneous coronary intervention (PCI) remain understudied. Our study sought to evaluate the impact of RA-PCI in patients with LV systolic dysfunction on long-term outcomes. Between 2015 and 2019, 4941 patients with reduced LV function (rEF) undergoing PCI (with or without RA) were included in the hospital database. The primary endpoint was in-hospital major adverse cardiovascular and cerebral events (MACCE). The secondary endpoint was 3-year MACCE. In-hospital MACCE rates were significantly higher in RA-PCI compared to standard PCI without RA (PCI) (7.6% vs. 3.9%, p = 0.0009). However, 3-years MACCE rates were similar in RA-PCI and PCI (26.40% vs. 26.6%, p = 0.948). In conclusion, RA-PCI in patients with rEF is feasible, safe, and shows similar long-term results to PCI. |
| doi_str_mv | 10.3390/jcm12175640 |
| format | Article |
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Our study sought to evaluate the impact of RA-PCI in patients with LV systolic dysfunction on long-term outcomes. Between 2015 and 2019, 4941 patients with reduced LV function (rEF) undergoing PCI (with or without RA) were included in the hospital database. The primary endpoint was in-hospital major adverse cardiovascular and cerebral events (MACCE). The secondary endpoint was 3-year MACCE. In-hospital MACCE rates were significantly higher in RA-PCI compared to standard PCI without RA (PCI) (7.6% vs. 3.9%, p = 0.0009). However, 3-years MACCE rates were similar in RA-PCI and PCI (26.40% vs. 26.6%, p = 0.948). In conclusion, RA-PCI in patients with rEF is feasible, safe, and shows similar long-term results to PCI.</description><identifier>ISSN: 2077-0383</identifier><identifier>EISSN: 2077-0383</identifier><identifier>DOI: 10.3390/jcm12175640</identifier><language>eng</language><publisher>MDPI AG</publisher><subject>Cardiac patients ; Care and treatment ; Comparative analysis ; Endarterectomy ; Health aspects ; Heart failure ; Left ventricular function ; Medical care ; Patient outcomes ; Quality management ; Safety and security measures ; Statistics ; Transluminal angioplasty</subject><ispartof>Journal of clinical medicine, 2023-08, Vol.12 (17)</ispartof><rights>COPYRIGHT 2023 MDPI AG</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Ayoub, Mohamed</creatorcontrib><creatorcontrib>Tajti, Péter</creatorcontrib><creatorcontrib>Akin, Ibrahim</creatorcontrib><creatorcontrib>Behnes, Michael</creatorcontrib><creatorcontrib>Schupp, Tobias</creatorcontrib><creatorcontrib>Forner, Jan</creatorcontrib><creatorcontrib>Omran, Hazem</creatorcontrib><creatorcontrib>Westermann, Dirk</creatorcontrib><creatorcontrib>Rudolph, Volker</creatorcontrib><creatorcontrib>Mashayekhi, Kambis</creatorcontrib><title>Safety and Long-Term Outcomes of Rotablation in Patients with Reduced</title><title>Journal of clinical medicine</title><description>Clinical outcomes in patients with reduced left ventricular systolic function undergoing rotational atherectomy (RA) for percutaneous coronary intervention (PCI) remain understudied. Our study sought to evaluate the impact of RA-PCI in patients with LV systolic dysfunction on long-term outcomes. Between 2015 and 2019, 4941 patients with reduced LV function (rEF) undergoing PCI (with or without RA) were included in the hospital database. The primary endpoint was in-hospital major adverse cardiovascular and cerebral events (MACCE). The secondary endpoint was 3-year MACCE. In-hospital MACCE rates were significantly higher in RA-PCI compared to standard PCI without RA (PCI) (7.6% vs. 3.9%, p = 0.0009). However, 3-years MACCE rates were similar in RA-PCI and PCI (26.40% vs. 26.6%, p = 0.948). In conclusion, RA-PCI in patients with rEF is feasible, safe, and shows similar long-term results to PCI.</description><subject>Cardiac patients</subject><subject>Care and treatment</subject><subject>Comparative analysis</subject><subject>Endarterectomy</subject><subject>Health aspects</subject><subject>Heart failure</subject><subject>Left ventricular function</subject><subject>Medical care</subject><subject>Patient outcomes</subject><subject>Quality management</subject><subject>Safety and security measures</subject><subject>Statistics</subject><subject>Transluminal angioplasty</subject><issn>2077-0383</issn><issn>2077-0383</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNptjMtqwzAQRUVpoSHNqj8g6NqpbL3sZQjpAwwpqfdhLI1chViCSKH072toF1lkZjGHy5lLyGPJlpw37PlgxrIqtVSC3ZBZxbQuGK_57QXfk0VKBzZNXYvJnZHNJzjMPxSCpW0MQ9HhaaTbczZxxESjo7uYoT9C9jFQH-jHRBhyot8-f9Ed2rNB-0DuHBwTLv7vnHQvm279VrTb1_f1qi0GpWXRaItcCAWG972QSvYlGGYdGOSuBkSmTV3JunQg0DVSVn2vQXKlBUNAzefk6a92gCPufXAxn8CMPpn9SitRKaUbOVnLK9a0FkdvYkDnp_zi4Rd3Rlyp</recordid><startdate>20230801</startdate><enddate>20230801</enddate><creator>Ayoub, Mohamed</creator><creator>Tajti, Péter</creator><creator>Akin, Ibrahim</creator><creator>Behnes, Michael</creator><creator>Schupp, Tobias</creator><creator>Forner, Jan</creator><creator>Omran, Hazem</creator><creator>Westermann, Dirk</creator><creator>Rudolph, Volker</creator><creator>Mashayekhi, Kambis</creator><general>MDPI AG</general><scope/></search><sort><creationdate>20230801</creationdate><title>Safety and Long-Term Outcomes of Rotablation in Patients with Reduced</title><author>Ayoub, Mohamed ; Tajti, Péter ; Akin, Ibrahim ; Behnes, Michael ; Schupp, Tobias ; Forner, Jan ; Omran, Hazem ; Westermann, Dirk ; Rudolph, Volker ; Mashayekhi, Kambis</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g675-97de3446ac3bb4565b1ac0dface3f8aee07c82581fa4ef9552bb7a536740eae73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Cardiac patients</topic><topic>Care and treatment</topic><topic>Comparative analysis</topic><topic>Endarterectomy</topic><topic>Health aspects</topic><topic>Heart failure</topic><topic>Left ventricular function</topic><topic>Medical care</topic><topic>Patient outcomes</topic><topic>Quality management</topic><topic>Safety and security measures</topic><topic>Statistics</topic><topic>Transluminal angioplasty</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ayoub, Mohamed</creatorcontrib><creatorcontrib>Tajti, Péter</creatorcontrib><creatorcontrib>Akin, Ibrahim</creatorcontrib><creatorcontrib>Behnes, Michael</creatorcontrib><creatorcontrib>Schupp, Tobias</creatorcontrib><creatorcontrib>Forner, Jan</creatorcontrib><creatorcontrib>Omran, Hazem</creatorcontrib><creatorcontrib>Westermann, Dirk</creatorcontrib><creatorcontrib>Rudolph, Volker</creatorcontrib><creatorcontrib>Mashayekhi, Kambis</creatorcontrib><jtitle>Journal of clinical medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ayoub, Mohamed</au><au>Tajti, Péter</au><au>Akin, Ibrahim</au><au>Behnes, Michael</au><au>Schupp, Tobias</au><au>Forner, Jan</au><au>Omran, Hazem</au><au>Westermann, Dirk</au><au>Rudolph, Volker</au><au>Mashayekhi, Kambis</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Safety and Long-Term Outcomes of Rotablation in Patients with Reduced</atitle><jtitle>Journal of clinical medicine</jtitle><date>2023-08-01</date><risdate>2023</risdate><volume>12</volume><issue>17</issue><issn>2077-0383</issn><eissn>2077-0383</eissn><abstract>Clinical outcomes in patients with reduced left ventricular systolic function undergoing rotational atherectomy (RA) for percutaneous coronary intervention (PCI) remain understudied. Our study sought to evaluate the impact of RA-PCI in patients with LV systolic dysfunction on long-term outcomes. Between 2015 and 2019, 4941 patients with reduced LV function (rEF) undergoing PCI (with or without RA) were included in the hospital database. The primary endpoint was in-hospital major adverse cardiovascular and cerebral events (MACCE). The secondary endpoint was 3-year MACCE. In-hospital MACCE rates were significantly higher in RA-PCI compared to standard PCI without RA (PCI) (7.6% vs. 3.9%, p = 0.0009). However, 3-years MACCE rates were similar in RA-PCI and PCI (26.40% vs. 26.6%, p = 0.948). In conclusion, RA-PCI in patients with rEF is feasible, safe, and shows similar long-term results to PCI.</abstract><pub>MDPI AG</pub><doi>10.3390/jcm12175640</doi></addata></record> |
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| source | MDPI - Multidisciplinary Digital Publishing Institute; PubMed Central; EZB Electronic Journals Library; PubMed Central Open Access |
| subjects | Cardiac patients Care and treatment Comparative analysis Endarterectomy Health aspects Heart failure Left ventricular function Medical care Patient outcomes Quality management Safety and security measures Statistics Transluminal angioplasty |
| title | Safety and Long-Term Outcomes of Rotablation in Patients with Reduced |
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