Molecular basis of interactions between CaMKII and a-actinin-2 that underlie dendritic spine enlargement

Ca /calmodulin-dependent protein kinase II (CaMKII) is essential for long-term potentiation (LTP) of excitatory synapses that is linked to learning and memory. In this study, we focused on understanding how interactions between CaMKIIα and the actin crosslinking protein α-actinin-2 underlie long-las...

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Veröffentlicht in:	eLife 2023-07, Vol.12
Hauptverfasser:	Curtis, Ashton J, Zhu, Jian, Penny, Christopher J, Gold, Matthew G
Format:	Artikel
Sprache:	eng
Schlagworte:	Calmodulin Calorimetry Muscle proteins Neurons Pharmaceutical industry Protein kinases
Online-Zugang:	Volltext
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