GTS-21 Enhances Regulatory T Cell Development from T Cell Receptor-Activated Human CD4[sup.+] T Cells Exhibiting Varied Levels of ICHRNA7/I and ICHRFAM7A/I Expression

Immune cells such as T cells and macrophages express α7 nicotinic acetylcholine receptors (α7 nAChRs), which contribute to the regulation of immune and inflammatory responses. Earlier findings suggest α7 nAChR activation promotes the development of regulatory T cells (Tregs) in mice. Using human CD4...

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Veröffentlicht in:International journal of molecular sciences 2023-07, Vol.24 (15)
Hauptverfasser: Mashimo, Masato, Fujii, Takeshi, Ono, Shiro, Moriwaki, Yasuhiro, Misawa, Hidemi, Azami, Tetsushi, Kasahara, Tadashi, Kawashima, Koichiro
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Sprache:eng
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