No Difference in the Prevalence of HIV-1 Igag/I Cytotoxic T-Lymphocyte-Associated Escape Mutations in Viral Sequences from Early and Late Parts of the HIV-1 Subtype C Pandemic in Botswana

HIV is known to accumulate escape mutations in the gag gene in response to the immune response from cytotoxic T lymphocytes (CTLs). These mutations can occur within an individual as well as at a population level. The population of Botswana exhibits a high prevalence of HLA*B57 and HLA*B58, which are...

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Veröffentlicht in:	Vaccines (Basel) 2023-05, Vol.11 (5)
Hauptverfasser:	Mokaleng, Baitshepi, Choga, Wonderful Tatenda, Bareng, Ontlametse Thato, Maruapula, Dorcas, Ditshwanelo, Doreen, Kelentse, Nametso, Mokgethi, Patrick, Moraka, Natasha Onalenna, Motswaledi, Modisa Sekhamo, Tawe, Leabaneng, Koofhethile, Catherine Kegakilwe, Moyo, Sikhulile, Zachariah, Matshediso, Gaseitsiwe, Simani
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Development and progression Distribution Health aspects HIV infection Immune response T cells
Online-Zugang:	Volltext
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