p38 and ERK1/2-Dependent Activation of c-Jun Is Required for the Downregulation of Oxidative Stress-Induced ER[alpha] in Hypothalamic Astrocytes

Introduction: Gonadotropin-releasing hormone (GnRH) is a hypothalamic neuropeptide that plays important roles in the female fertility. Accumulating evidence suggests that ER[alpha] present in the astrocytes of the hypothalamus region is essential for production of GnRH. The astrocytes display age-re...

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Veröffentlicht in:	Neuroendocrinology 2023-07, Vol.113 (7), p.756
Hauptverfasser:	Dai, Xiaoman, Lin, Anlan, Mi, Xue, Ke, Yilang, Zhang, Jing, Chen, Xiaochun
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Estrogen Genes Genetic transcription Oxidative stress Pituitary hormones
Online-Zugang:	Volltext
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