Boosting the Antibacterial Activity of Azithromycin on Multidrug-Resistant IEscherichia coli/I by Efflux Pump Inhibition Coupled with Outer Membrane Permeabilization Induced by Phenylalanine-Arginine β-Naphthylamide

The global spread of multidrug-resistant (MDR) bacteria increases the demand for the discovery of new antibiotics and adjuvants. Phenylalanine-arginine β-naphthylamide (PAβN) is an inhibitor of efflux pumps in Gram-negative bacteria, such as the AcrAB-TolC complex in Escherichia coli. We aimed to ex...

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Veröffentlicht in:	International journal of molecular sciences 2023-05, Vol.24 (10)
Hauptverfasser:	Al-Marzooq, Farah, Ghazawi, Akela, Daoud, Lana, Tariq, Saeed
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibacterial agents Arginine Azithromycin Bacteria Drug resistance in microorganisms Permeability Tetracycline Tetracyclines
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