Isosinensetin Stimulates Glucagon-like Peptide-1 Secretion via Activation of hTAS2R50 and the G[sub.βγ]-Mediated Signaling Pathway

Bitter taste receptors (TAS2Rs) are G protein-coupled receptors localized in the taste buds of the tongue. They may also be present in non-lingual organs, including the brain, lung, kidney, and gastrointestinal (GI) tract. Recent studies on bitter taste receptor functions have suggested TAS2Rs as po...

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Veröffentlicht in:	International journal of molecular sciences 2023-02, Vol.24 (4)
Hauptverfasser:	Lee, Seung-Hyeon, Ko, Hyun Min, Jee, Wona, Kim, Hyungsuk, Chung, Won-Seok, Jang, Hyeung-Jin
Format:	Artikel
Sprache:	eng
Schlagworte:	Cellular signal transduction Gastrointestinal system Glucagon Taste Type 2 diabetes
Online-Zugang:	Volltext
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