A Case Report of Early-Onset Alzheimer’s Disease Using [sup.18]F-FDG PET and [sup.18]F-FBB PET
We describe a 40-year-old female patient who presented with sleep disturbance, intermittent headache, and gradual subjective cognitive decline. [sup.18]F-fluorodeoxyglucose (FDG) positron emission tomography (PET) showed mild FDG hypometabolism in bilateral parietal and temporal lobes. However, [sup...
Gespeichert in:
| Veröffentlicht in: | Diagnostics (Basel) 2023-05, Vol.13 (10) |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 10 |
| container_start_page | |
| container_title | Diagnostics (Basel) |
| container_volume | 13 |
| creator | Yoo, Jang Cheon, Miju Kang, Min-Ju |
| description | We describe a 40-year-old female patient who presented with sleep disturbance, intermittent headache, and gradual subjective cognitive decline. [sup.18]F-fluorodeoxyglucose (FDG) positron emission tomography (PET) showed mild FDG hypometabolism in bilateral parietal and temporal lobes. However, [sup.18]F-florbetaben (FBB) amyloid PET revealed diffuse amyloid retention in the lateral temporal cortex, frontal cortex, posterior cingulate cortex/precuneus, parietal cortex, and cerebellum. This finding supports the clinical significance of amyloid imaging in diagnostic work-up of early-onset Alzheimer's disease (EOAD). |
| doi_str_mv | 10.3390/diagnostics13101671 |
| format | Article |
| fullrecord | <record><control><sourceid>gale</sourceid><recordid>TN_cdi_gale_infotracmisc_A750888969</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A750888969</galeid><sourcerecordid>A750888969</sourcerecordid><originalsourceid>FETCH-LOGICAL-g137t-547c63bf04914991382bea8316aaaa2e9ee24cf2077001d5fce9c6e1995fd163</originalsourceid><addsrcrecordid>eNptj01OwzAQhS0EElXpCdhYYp3iifNjL9NfkCoVobBCqLjOOBilThWHRVlxDa7HSUiBRRa8Wczo6ZunGUIugY05l-y6sKp0tW-t9sCBQZLCCRmELI2DKAJx2pvPycj7V9ZJAhdhPCDPGZ0qj_Qe93XT0trQuWqqQ7B2HluaVe8vaHfYfH18ejqzHo_sg7eupI_-bT8G8bQIFrMlvZvnVLmi704mR_eCnBlVeRz99SHJF_N8ehOs1svbabYKSuBpG8RRqhO-NSySEMmf67aoBIdEdQpRIoaRNt0nKWNQxEaj1AmClLEpIOFDcvUbW6oKN9aZum2U3lmvN1kaMyGETGRHjf-huipwZ3Xt0NjO7y18A0CoZm0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>A Case Report of Early-Onset Alzheimer’s Disease Using [sup.18]F-FDG PET and [sup.18]F-FBB PET</title><source>DOAJ Directory of Open Access Journals</source><source>PubMed Central Open Access</source><source>MDPI - Multidisciplinary Digital Publishing Institute</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Yoo, Jang ; Cheon, Miju ; Kang, Min-Ju</creator><creatorcontrib>Yoo, Jang ; Cheon, Miju ; Kang, Min-Ju</creatorcontrib><description>We describe a 40-year-old female patient who presented with sleep disturbance, intermittent headache, and gradual subjective cognitive decline. [sup.18]F-fluorodeoxyglucose (FDG) positron emission tomography (PET) showed mild FDG hypometabolism in bilateral parietal and temporal lobes. However, [sup.18]F-florbetaben (FBB) amyloid PET revealed diffuse amyloid retention in the lateral temporal cortex, frontal cortex, posterior cingulate cortex/precuneus, parietal cortex, and cerebellum. This finding supports the clinical significance of amyloid imaging in diagnostic work-up of early-onset Alzheimer's disease (EOAD).</description><identifier>ISSN: 2075-4418</identifier><identifier>EISSN: 2075-4418</identifier><identifier>DOI: 10.3390/diagnostics13101671</identifier><language>eng</language><publisher>MDPI AG</publisher><subject>Alzheimer's disease ; PET imaging ; Pets ; Sleep disorders</subject><ispartof>Diagnostics (Basel), 2023-05, Vol.13 (10)</ispartof><rights>COPYRIGHT 2023 MDPI AG</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,864,27922,27923</link.rule.ids></links><search><creatorcontrib>Yoo, Jang</creatorcontrib><creatorcontrib>Cheon, Miju</creatorcontrib><creatorcontrib>Kang, Min-Ju</creatorcontrib><title>A Case Report of Early-Onset Alzheimer’s Disease Using [sup.18]F-FDG PET and [sup.18]F-FBB PET</title><title>Diagnostics (Basel)</title><description>We describe a 40-year-old female patient who presented with sleep disturbance, intermittent headache, and gradual subjective cognitive decline. [sup.18]F-fluorodeoxyglucose (FDG) positron emission tomography (PET) showed mild FDG hypometabolism in bilateral parietal and temporal lobes. However, [sup.18]F-florbetaben (FBB) amyloid PET revealed diffuse amyloid retention in the lateral temporal cortex, frontal cortex, posterior cingulate cortex/precuneus, parietal cortex, and cerebellum. This finding supports the clinical significance of amyloid imaging in diagnostic work-up of early-onset Alzheimer's disease (EOAD).</description><subject>Alzheimer's disease</subject><subject>PET imaging</subject><subject>Pets</subject><subject>Sleep disorders</subject><issn>2075-4418</issn><issn>2075-4418</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNptj01OwzAQhS0EElXpCdhYYp3iifNjL9NfkCoVobBCqLjOOBilThWHRVlxDa7HSUiBRRa8Wczo6ZunGUIugY05l-y6sKp0tW-t9sCBQZLCCRmELI2DKAJx2pvPycj7V9ZJAhdhPCDPGZ0qj_Qe93XT0trQuWqqQ7B2HluaVe8vaHfYfH18ejqzHo_sg7eupI_-bT8G8bQIFrMlvZvnVLmi704mR_eCnBlVeRz99SHJF_N8ehOs1svbabYKSuBpG8RRqhO-NSySEMmf67aoBIdEdQpRIoaRNt0nKWNQxEaj1AmClLEpIOFDcvUbW6oKN9aZum2U3lmvN1kaMyGETGRHjf-huipwZ3Xt0NjO7y18A0CoZm0</recordid><startdate>20230501</startdate><enddate>20230501</enddate><creator>Yoo, Jang</creator><creator>Cheon, Miju</creator><creator>Kang, Min-Ju</creator><general>MDPI AG</general><scope/></search><sort><creationdate>20230501</creationdate><title>A Case Report of Early-Onset Alzheimer’s Disease Using [sup.18]F-FDG PET and [sup.18]F-FBB PET</title><author>Yoo, Jang ; Cheon, Miju ; Kang, Min-Ju</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g137t-547c63bf04914991382bea8316aaaa2e9ee24cf2077001d5fce9c6e1995fd163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Alzheimer's disease</topic><topic>PET imaging</topic><topic>Pets</topic><topic>Sleep disorders</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yoo, Jang</creatorcontrib><creatorcontrib>Cheon, Miju</creatorcontrib><creatorcontrib>Kang, Min-Ju</creatorcontrib><jtitle>Diagnostics (Basel)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yoo, Jang</au><au>Cheon, Miju</au><au>Kang, Min-Ju</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Case Report of Early-Onset Alzheimer’s Disease Using [sup.18]F-FDG PET and [sup.18]F-FBB PET</atitle><jtitle>Diagnostics (Basel)</jtitle><date>2023-05-01</date><risdate>2023</risdate><volume>13</volume><issue>10</issue><issn>2075-4418</issn><eissn>2075-4418</eissn><abstract>We describe a 40-year-old female patient who presented with sleep disturbance, intermittent headache, and gradual subjective cognitive decline. [sup.18]F-fluorodeoxyglucose (FDG) positron emission tomography (PET) showed mild FDG hypometabolism in bilateral parietal and temporal lobes. However, [sup.18]F-florbetaben (FBB) amyloid PET revealed diffuse amyloid retention in the lateral temporal cortex, frontal cortex, posterior cingulate cortex/precuneus, parietal cortex, and cerebellum. This finding supports the clinical significance of amyloid imaging in diagnostic work-up of early-onset Alzheimer's disease (EOAD).</abstract><pub>MDPI AG</pub><doi>10.3390/diagnostics13101671</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2075-4418 |
| ispartof | Diagnostics (Basel), 2023-05, Vol.13 (10) |
| issn | 2075-4418 2075-4418 |
| language | eng |
| recordid | cdi_gale_infotracmisc_A750888969 |
| source | DOAJ Directory of Open Access Journals; PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Alzheimer's disease PET imaging Pets Sleep disorders |
| title | A Case Report of Early-Onset Alzheimer’s Disease Using [sup.18]F-FDG PET and [sup.18]F-FBB PET |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T22%3A39%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20Case%20Report%20of%20Early-Onset%20Alzheimer%E2%80%99s%20Disease%20Using%20%5Bsup.18%5DF-FDG%20PET%20and%20%5Bsup.18%5DF-FBB%20PET&rft.jtitle=Diagnostics%20(Basel)&rft.au=Yoo,%20Jang&rft.date=2023-05-01&rft.volume=13&rft.issue=10&rft.issn=2075-4418&rft.eissn=2075-4418&rft_id=info:doi/10.3390/diagnostics13101671&rft_dat=%3Cgale%3EA750888969%3C/gale%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_galeid=A750888969&rfr_iscdi=true |