Synthesis and Biological Evaluation of IO/I[sup.6]-Aminoalkyl-Hispidol Analogs as Multifunctional Monoamine Oxidase-B Inhibitors towards Management of Neurodegenerative Diseases

Oxidative catabolism of monoamine neurotransmitters by monoamine oxidases (MAOs) produces reactive oxygen species (ROS), which contributes to neuronal cells' death and also lowers monoamine neurotransmitter levels. In addition, acetylcholinesterase activity and neuroinflammation are involved in...

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Veröffentlicht in:	Antioxidants 2023-04, Vol.12 (5)
Hauptverfasser:	Hassan, Ahmed H. E, Kim, Hyeon Jeong, Park, Keontae, Choi, Yeonwoo, Moon, Suyeon, Lee, Chae Hyeon, Kim, Yeon Ju, Cho, Soo Bin, Gee, Min Sung, Lee, Danbi, Park, Jong-Hyun, Lee, Jong Kil, Ryu, Jong Hoon, Park, Ki Duk, Lee, Yong Sup
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Analysis Nervous system diseases
Online-Zugang:	Volltext
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