The Pesticide Chlordecone Promotes Parkinsonism-like Neurodegeneration with Tau Lesions in Midbrain Cultures and IC. elegans/I Worms

Chlordecone (CLD) is an organochlorine pesticide (OCP) that is currently banned but still contaminates ecosystems in the French Caribbean. Because OCPs are known to increase the risk of Parkinson’s disease (PD), we tested whether chronic low-level intoxication with CLD could reproduce certain key ch...

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Veröffentlicht in:	Cells (Basel, Switzerland) Switzerland), 2023-05, Vol.12 (9)
Hauptverfasser:	Parrales-Macias, Valeria, Michel, Patrick P, Tourville, Aurore, Raisman-Vozari, Rita, Haïk, Stéphane, Hunot, Stéphane, Bizat, Nicolas, Lannuzel, Annie
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell culture Development and progression Environmental aspects Health aspects Organochlorine compounds Parkinsonism Pesticides Risk factors Tau proteins
Online-Zugang:	Volltext
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