S- is Not a Selective Inhibitor of Equilibrative Nucleoside Transporters but Also Blocks Efflux Activity of Breast Cancer Resistance Protein

Purpose S-(4-Nitrobenzyl)-6-thioinosine (NBMPR) is routinely used at concentrations of 0.10 [mu]M and 0.10 mM to specifically inhibit transport of nucleosides mediated by equilibrative nucleoside transporters 1 (ENT1) and 2 (ENT2), respectively. We recently showed that NBMPR (0.10 mM) might also inh...

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Veröffentlicht in:	Pharmaceutical research 2020-03, Vol.37 (3)
Hauptverfasser:	Karbanova, Sara, Sorf, Ales, Jiraskova, Lucie, Lalinska, Anezka, Ptackova, Zuzana, Staud, Frantisek, Cerveny, Lukas
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Breast cancer Glibenclamide Tenofovir Zidovudine
Online-Zugang:	Volltext
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