The Tritiated Water Skin Barrier Integrity Test: Considerations for Acceptance Criteria with and Without .sup.14C-Octanol

Purpose A study was designed to assess barrier integrity simultaneously using separate compounds (probes) for polar and non-polar pathways through the skin, .sup.3H.sub.2O and .sup.14C-octanol, respectively; and to determine whether the two probe approach could better define barrier integrity. Metho...

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Veröffentlicht in:	Pharmaceutical research 2017-01, Vol.34 (1), p.217
Hauptverfasser:	Lehman, Paul A, Beatch, Kacie, Raney, Sam G, Franz, Thomas J
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Medical tests Skin
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