Integrated Analysis of Transcriptome and microRNA Profile Reveals the Toxicity of IEuphorbia/I Factors toward Human Colon Adenocarcinoma Cell Line Caco-2

Euphorbia factors, lathyrane-type diterpenoids isolated from the medical herb Euphorbia lathyris L. (Euphorbiaceae), have been associated with intestinal irritation toxicity, but the mechanisms underlying this phenomenon are still unknown. The objective of this study was to evaluate the transcriptom...

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Veröffentlicht in:	Molecules (Basel, Switzerland) Switzerland), 2022-10, Vol.27 (20)
Hauptverfasser:	Zou, Lingyue, Bao, Wenqiang, Gao, Yadong, Chen, Mengting, Wu, Yajiao, Wang, Shuo, Li, Chutao, Zhang, Jian, Zhang, Dongcheng, Wang, Qi, Zhu, An
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Analysis Cellular signal transduction Colon cancer Gene expression Genes Genetic polymorphisms Genomics Messenger RNA MicroRNA T cells
Online-Zugang:	Volltext
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