BAM15 Relieves Neurodegeneration in Aged ICaenorhabditis elegans/I and Extends Lifespan

BAM15 was recently screened as a protonophore uncoupler specifically for the mitochondrial membrane but not the plasma membrane. It is equally as potent as FCCP, but less toxic. Previously, mitochondrial uncoupling via DNP alleviates neurodegeneration in the nematode Caenorhabditis elegans during ag...

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Veröffentlicht in:Metabolites 2022-11, Vol.12 (11)
Hauptverfasser: Cho, Injeong, Song, Hyun-Ok, Ji, Ha Eun, Yang, Sungtae, Cho, Jeong Hoon
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Sprache:eng
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