tRNA-like Transcripts from the INEAT1-MALAT1/I Genomic Region Critically Influence Human Innate Immunity and Macrophage Functions

The evolutionary conserved NEAT1-MALAT1 gene cluster generates large noncoding transcripts remaining nuclear, while tRNA-like transcripts (mascRNA, menRNA) enzymatically generated from these precursors translocate to the cytosol. Whereas functions have been assigned to the nuclear transcripts, data...

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Veröffentlicht in:	Cells (Basel, Switzerland) Switzerland), 2022-12, Vol.11 (24)
Hauptverfasser:	Gast, Ma, Nageswaran, Vanasa, Kuss, Andreas W, Tzvetkova, Ana, Wang, Xiaomin, Mochmann, Liliana H, Rad, Pegah Ramezani, Weiss, Stefan, Simm, Stefan, Zeller, Tanja, Voelzke, Henry, Hoffmann, Wolfgang, Völker, Uwe, Felix, Stefan B, Dörr, Marcus, Beling, Antje, Skurk, Carsten, Leistner, David-Manuel, Rauch, Bernhard H, Hirose, Tetsuro, Heidecker, Bettina, Klingel, Karin, Nakagawa, Shinichi, Poller, Wolfram C, Swirski, Filip K, Haghikia, Arash, Poller, Wolfgang
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Care and treatment Complications and side effects Heart attack Inflammation Macrophages Transfer RNA
Online-Zugang:	Volltext
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