F]NOS PET Brain Imaging Suggests Elevated Neuroinflammation in Idiopathic Parkinson’s Disease

Neuroinflammation is implicated as a key pathologic mechanism in many neurodegenerative diseases and is thought to be mediated in large part by microglia, native phagocytic immune cells of the CNS. Abnormal aggregation of the protein α-synuclein after phagocytosis by microglia is one possible neurop...

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Veröffentlicht in:Cells (Basel, Switzerland) Switzerland), 2022-09, Vol.11 (19)
Hauptverfasser: Doot, Robert K, Young, Anthony J, Nasrallah, Ilya M, Wetherill, Reagan R, Siderowf, Andrew, Mach, Robert H, Dubroff, Jacob G
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Sprache:eng
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