Inhibiting ILeishmania donovani/I Sterol Methyltransferase to Identify Lead Compounds Using Molecular Modelling

The recent outlook of leishmaniasis as a global public health concern coupled with the reportage of resistance and lack of efficacy of most antileishmanial drugs calls for a concerted effort to find new leads. The study combined In silico and in vitro approaches to identify novel potential synthetic...

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Veröffentlicht in:	Pharmaceuticals (Basel, Switzerland) Switzerland), 2023-02, Vol.16 (3)
Hauptverfasser:	Sakyi, Patrick O, Kwofie, Samuel K, Tuekpe, Julius K, Gwira, Theresa M, Broni, Emmanuel, Miller, Whelton A, Wilson, Michael D, Amewu, Richard K
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiparasitic agents Causes of Chemical properties Dosage and administration Drug therapy Leishmaniasis Testing
Online-Zugang:	Volltext
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