Host-Guest Complex of Cucurbituril with 5-Fluorouracil: Structural Study, Effect on Cytotoxicity, and Intracellular ROS Generation

Cucurbiturils are magnificent macrocycles that are used as precise molecules for the fabrication of supramolecular chemotherapeutic agents through host-guest molecular recognition. In the present work, the host-guest complex of cucurbit[6]uril (CB[6]) with 5-fluorouracil (Flu, an anticancer drug) is...

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Veröffentlicht in:	Pharmaceutical chemistry journal 2023-02, Vol.56 (11), p.1526-1534
Hauptverfasser:	Priya, T. Jaba, Sugumar, R. Wilfred, Harini, M., Prasad, N. Rajendra
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Chemotherapy Drug delivery systems Drugs Fluorouracil Medicine Organic Chemistry Pharmacology/Toxicology Pharmacy Vehicles
Online-Zugang:	Volltext
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