Structure, signal transduction, activation, and inhibition of integrin [alpha]IIb[beta]3

Integrins are heterodimeric receptors comprising [alpha] and [beta] subunits. They are expressed on the cell surface and play key roles in cell adhesion, migration, and growth. Several types of integrins are expressed on the platelets, including [alpha]v[beta]3, [alpha]IIb[beta]3, [alpha]2[beta]1, [...

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Veröffentlicht in:Thrombosis journal 2023-02, Vol.21 (1)
Hauptverfasser: Xin, Honglei, Huang, Jiansong, Song, Zhiqun, Mao, Jianhua, Xi, Xiaodong, Shi, Xiaofeng
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Sprache:eng
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