Combined Treatment with Fluoride and Antimicrobial Peptide GH12 Efficiently Controls Caries in vitro and in vivo

Combining fluoride and antimicrobial agents enhances regulation of acid and exopolysaccharide production by biofilms. The combination also weakens the acidogenic and aciduric bacteria that contribute to caries, achieving stronger caries-controlling effects with lower concentrations of fluoride. In p...

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Veröffentlicht in:	Caries research 2023-02, Vol.56 (5-6), p.524-534
Hauptverfasser:	Wang, Yufei, Zeng, Yuhao, Feng, Zening, Li, Zhongxu, Jiang, Xuelian, Han, Sili, Washio, Jumpei, Takahashi, Nobuhiro, Zhang, Linglin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antimicrobial Peptides - pharmacology Antimicrobial Peptides - therapeutic use Bacteria Biofilms Carbenicillin Cattle Dental caries Dental Caries - drug therapy Dental Caries - microbiology Dental Caries - prevention & control Dental Caries Susceptibility Dental Plaque - drug therapy Dental Plaque - microbiology Fluoride treatment Fluorides Fluorides - pharmacology Lactic Acid Microbiota (Symbiotic organisms) Peptides Rats Research Article RNA, Ribosomal, 16S Sodium Fluoride - pharmacology Streptococcus mutans
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