SYSTEMATIC REVIEW AND META-ANALYSIS ABOUT THE EFFECTS OF ENDURANCE TRAINING AND WHEY PROTEIN SUPPLEMENTATION ON GENE EXPRESSION OF MTOR, MURF-1, MAFBX/Revisão sistemática e meta-análise sobre os efeitos do treinamento de endurance e da suplementação de whey protein sobre a expressão gênica de MTOR, MURF-1, MAFBX

Aim: Systematic review and meta-analysis about the effects of endurance training and Whey Protein supplementation on the gene expression of MTOR, MURF-1, MAFBX. Materials and methods: To this systematic review was used the concepts of systematic review and meta-analysis proposed by Thomas, Nelson, Silverman (2012), and Berwanger et al., (2007), and the search followed procedures proposed by Navarro and Navarro (2012), and for the criteria of evaluation of the technical and scientific quality of the texts was used the scale proposed by Galna et al., (2009). Results and discursion: From 724 eligible studies, the sample was 4 original articles where we inferred that the models of endurance training adopted in the experiments, are, the following: Jump in liquid environment, motorized treadmill, and, in squatting apparatus for electric stimulation in the base and that in terms of experimental study in relation to the dose of the supplement, the prescribed was recommended by manuals; and about the gene expression of MTOR, MURF-1, MAFBX, although had been verified it does not occurred due the endurance training and the Whey Protein supplementation and, therefore, absent. Conclusion: In terms of experimentation, it's not found studies enough to compose the adequate procedure for a meta-analysis, even after a systematic review about the effects of endurance training and Whey Protein supplementation on the gene expression of MTOR, protein synthesis and the gene expression of MURF-1, MAFBx of protein degradation in wistar rats. Key words: Endurance training. Whey Proteins. MTOR. MURF-1. MAFBX. Objetivo: Revisão sistemática e meta-análise sobre os efeitos do treinamento de resistência e suplementação de Whey Protein na expressão gênica de MTOR, MURF-1, MAFBX. Materiais e métodos: Para esta revisão sistemática foram utilizados os conceitos de revisão sistemática e metanálise propostos por Thomas, Nelson, Silverman (2012), e Berwanger et al., (2007), e a busca seguiu os procedimentos propostos por Navarro e Navarro (2012), e para os critérios de avaliação da qualidade técnica e científica dos textos foi utilizada a escala proposta por Galna et al., (2009). Resultados e discussão: A partir de 724 estudos elegíveis, a amostra foi de 4 artigos originais onde inferimos que os modelos de treinamento de endurance adotados nos experimentos, são, os seguintes: Salto em meio líquido, esteira motorizada, e, em agachamento aparelho para eletroestimulação na base e que em termos de