LIPID ABNORMALITIES, LIPOPROTEIN AND APOPROTEIN PATTERN IN NON-DIALYZED PATIENTS WITH CHRONIC KIDNEY DISEASE
The present study was carried out to explore the altered lipid, lipoprotein and apoprotein abnormalities along with lipoprotein (a) in chronic kidney disease patients with stage I to V which were further divided into group 1 (stage I and II), group 2 (stage III and IV) and group 3 (stage V). 50 chro...
Gespeichert in:
| Veröffentlicht in: | Indian journal of clinical biochemistry 2022-05, Vol.25 (1), p.47 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 1 |
| container_start_page | 47 |
| container_title | Indian journal of clinical biochemistry |
| container_volume | 25 |
| creator | Rao, A.M Bitla, A.R Reddy, E.P Sivakumar, V Rao, P.V.L.N.Srinivasa |
| description | The present study was carried out to explore the altered lipid, lipoprotein and apoprotein abnormalities along with lipoprotein (a) in chronic kidney disease patients with stage I to V which were further divided into group 1 (stage I and II), group 2 (stage III and IV) and group 3 (stage V). 50 chronic kidney disease patients with stage I to V and 20 healthy normal subjects as controls were recruited for this study. Among the various parameters tested triglyceride levels were high in group 1 and 2, whereas VLDL cholesterol, Lp (a) and apo B levels were significantly high in all the groups when compared to controls (P |
| format | Article |
| fullrecord | <record><control><sourceid>gale</sourceid><recordid>TN_cdi_gale_infotracmisc_A734897317</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A734897317</galeid><sourcerecordid>A734897317</sourcerecordid><originalsourceid>FETCH-LOGICAL-g677-7b4cc049b37cba5e5e03f149523bbd64ca03b10e3b842f478d21e9b5e98efacd3</originalsourceid><addsrcrecordid>eNptjEFLxDAQhXtQcF39DwGvVpIm3TTH2EYbrElpA7JeliRNl0p3F6z_HyMKepA5zHvfvDdnyQoyClPEUH6RXC7LG4SYQIJWydzIVlaA3yvdPfNGGin6WxChbjtthFSAq3j-tS03RnQKRKm0SivJm-2rqL64FMr04EWaGpR1p5UswZOslNiCSvaC9-IqOR_tvITrn71OzIMwZZ02-lGWvEn3G0pT6oj3kDCHqXc2D3mAeESE5Rl2btgQbyF2CAbsCpKNhBZDhgJzeWBFGK0f8Dq5-X67t3PYTcfx9PFu_WFa_I5TTApGMaIxdfdPKs4QDpM_HcM4Rf6n8AkT6Vn3</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>LIPID ABNORMALITIES, LIPOPROTEIN AND APOPROTEIN PATTERN IN NON-DIALYZED PATIENTS WITH CHRONIC KIDNEY DISEASE</title><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>SpringerLink Journals - AutoHoldings</source><creator>Rao, A.M ; Bitla, A.R ; Reddy, E.P ; Sivakumar, V ; Rao, P.V.L.N.Srinivasa</creator><creatorcontrib>Rao, A.M ; Bitla, A.R ; Reddy, E.P ; Sivakumar, V ; Rao, P.V.L.N.Srinivasa</creatorcontrib><description>The present study was carried out to explore the altered lipid, lipoprotein and apoprotein abnormalities along with lipoprotein (a) in chronic kidney disease patients with stage I to V which were further divided into group 1 (stage I and II), group 2 (stage III and IV) and group 3 (stage V). 50 chronic kidney disease patients with stage I to V and 20 healthy normal subjects as controls were recruited for this study. Among the various parameters tested triglyceride levels were high in group 1 and 2, whereas VLDL cholesterol, Lp (a) and apo B levels were significantly high in all the groups when compared to controls (P<0.05). However, LDL cholesterol level was significantly low in group 3 only as compared to control group (P<0.05). Apoprotein AI values also showed significant decrease in all groups as compared to controls (P<0.05). Though total cholesterol levels in group 1 and LDL levels in group 1 and 2 were higher than controls, but the values attained not statistically significant (P>0.05). In conclusion high levels of VLDL cholesterol, Lp (a), apo B and low levels of apoprotein AI as reported in this study are the major lipid disorders in the development of cardiovascular complications at all the stages in these patients. KEY WORDS Chronic Kidney Disease, End stage renal disease, Lipid Profile, Lp(a), Lipoprotein Metabolism.</description><identifier>ISSN: 0970-1915</identifier><language>eng</language><publisher>Springer</publisher><subject>Blood cholesterol ; Chronic kidney failure ; Development and progression ; Lipoprotein A ; Low density lipoproteins ; Medical research ; Medicine, Experimental ; Physiological aspects ; Trans fatty acids ; Triglycerides</subject><ispartof>Indian journal of clinical biochemistry, 2022-05, Vol.25 (1), p.47</ispartof><rights>COPYRIGHT 2022 Springer</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids></links><search><creatorcontrib>Rao, A.M</creatorcontrib><creatorcontrib>Bitla, A.R</creatorcontrib><creatorcontrib>Reddy, E.P</creatorcontrib><creatorcontrib>Sivakumar, V</creatorcontrib><creatorcontrib>Rao, P.V.L.N.Srinivasa</creatorcontrib><title>LIPID ABNORMALITIES, LIPOPROTEIN AND APOPROTEIN PATTERN IN NON-DIALYZED PATIENTS WITH CHRONIC KIDNEY DISEASE</title><title>Indian journal of clinical biochemistry</title><description>The present study was carried out to explore the altered lipid, lipoprotein and apoprotein abnormalities along with lipoprotein (a) in chronic kidney disease patients with stage I to V which were further divided into group 1 (stage I and II), group 2 (stage III and IV) and group 3 (stage V). 50 chronic kidney disease patients with stage I to V and 20 healthy normal subjects as controls were recruited for this study. Among the various parameters tested triglyceride levels were high in group 1 and 2, whereas VLDL cholesterol, Lp (a) and apo B levels were significantly high in all the groups when compared to controls (P<0.05). However, LDL cholesterol level was significantly low in group 3 only as compared to control group (P<0.05). Apoprotein AI values also showed significant decrease in all groups as compared to controls (P<0.05). Though total cholesterol levels in group 1 and LDL levels in group 1 and 2 were higher than controls, but the values attained not statistically significant (P>0.05). In conclusion high levels of VLDL cholesterol, Lp (a), apo B and low levels of apoprotein AI as reported in this study are the major lipid disorders in the development of cardiovascular complications at all the stages in these patients. KEY WORDS Chronic Kidney Disease, End stage renal disease, Lipid Profile, Lp(a), Lipoprotein Metabolism.</description><subject>Blood cholesterol</subject><subject>Chronic kidney failure</subject><subject>Development and progression</subject><subject>Lipoprotein A</subject><subject>Low density lipoproteins</subject><subject>Medical research</subject><subject>Medicine, Experimental</subject><subject>Physiological aspects</subject><subject>Trans fatty acids</subject><subject>Triglycerides</subject><issn>0970-1915</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNptjEFLxDAQhXtQcF39DwGvVpIm3TTH2EYbrElpA7JeliRNl0p3F6z_HyMKepA5zHvfvDdnyQoyClPEUH6RXC7LG4SYQIJWydzIVlaA3yvdPfNGGin6WxChbjtthFSAq3j-tS03RnQKRKm0SivJm-2rqL64FMr04EWaGpR1p5UswZOslNiCSvaC9-IqOR_tvITrn71OzIMwZZ02-lGWvEn3G0pT6oj3kDCHqXc2D3mAeESE5Rl2btgQbyF2CAbsCpKNhBZDhgJzeWBFGK0f8Dq5-X67t3PYTcfx9PFu_WFa_I5TTApGMaIxdfdPKs4QDpM_HcM4Rf6n8AkT6Vn3</recordid><startdate>20220524</startdate><enddate>20220524</enddate><creator>Rao, A.M</creator><creator>Bitla, A.R</creator><creator>Reddy, E.P</creator><creator>Sivakumar, V</creator><creator>Rao, P.V.L.N.Srinivasa</creator><general>Springer</general><scope/></search><sort><creationdate>20220524</creationdate><title>LIPID ABNORMALITIES, LIPOPROTEIN AND APOPROTEIN PATTERN IN NON-DIALYZED PATIENTS WITH CHRONIC KIDNEY DISEASE</title><author>Rao, A.M ; Bitla, A.R ; Reddy, E.P ; Sivakumar, V ; Rao, P.V.L.N.Srinivasa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g677-7b4cc049b37cba5e5e03f149523bbd64ca03b10e3b842f478d21e9b5e98efacd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Blood cholesterol</topic><topic>Chronic kidney failure</topic><topic>Development and progression</topic><topic>Lipoprotein A</topic><topic>Low density lipoproteins</topic><topic>Medical research</topic><topic>Medicine, Experimental</topic><topic>Physiological aspects</topic><topic>Trans fatty acids</topic><topic>Triglycerides</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rao, A.M</creatorcontrib><creatorcontrib>Bitla, A.R</creatorcontrib><creatorcontrib>Reddy, E.P</creatorcontrib><creatorcontrib>Sivakumar, V</creatorcontrib><creatorcontrib>Rao, P.V.L.N.Srinivasa</creatorcontrib><jtitle>Indian journal of clinical biochemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rao, A.M</au><au>Bitla, A.R</au><au>Reddy, E.P</au><au>Sivakumar, V</au><au>Rao, P.V.L.N.Srinivasa</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>LIPID ABNORMALITIES, LIPOPROTEIN AND APOPROTEIN PATTERN IN NON-DIALYZED PATIENTS WITH CHRONIC KIDNEY DISEASE</atitle><jtitle>Indian journal of clinical biochemistry</jtitle><date>2022-05-24</date><risdate>2022</risdate><volume>25</volume><issue>1</issue><spage>47</spage><pages>47-</pages><issn>0970-1915</issn><abstract>The present study was carried out to explore the altered lipid, lipoprotein and apoprotein abnormalities along with lipoprotein (a) in chronic kidney disease patients with stage I to V which were further divided into group 1 (stage I and II), group 2 (stage III and IV) and group 3 (stage V). 50 chronic kidney disease patients with stage I to V and 20 healthy normal subjects as controls were recruited for this study. Among the various parameters tested triglyceride levels were high in group 1 and 2, whereas VLDL cholesterol, Lp (a) and apo B levels were significantly high in all the groups when compared to controls (P<0.05). However, LDL cholesterol level was significantly low in group 3 only as compared to control group (P<0.05). Apoprotein AI values also showed significant decrease in all groups as compared to controls (P<0.05). Though total cholesterol levels in group 1 and LDL levels in group 1 and 2 were higher than controls, but the values attained not statistically significant (P>0.05). In conclusion high levels of VLDL cholesterol, Lp (a), apo B and low levels of apoprotein AI as reported in this study are the major lipid disorders in the development of cardiovascular complications at all the stages in these patients. KEY WORDS Chronic Kidney Disease, End stage renal disease, Lipid Profile, Lp(a), Lipoprotein Metabolism.</abstract><pub>Springer</pub></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0970-1915 |
| ispartof | Indian journal of clinical biochemistry, 2022-05, Vol.25 (1), p.47 |
| issn | 0970-1915 |
| language | eng |
| recordid | cdi_gale_infotracmisc_A734897317 |
| source | EZB-FREE-00999 freely available EZB journals; PubMed Central; SpringerLink Journals - AutoHoldings |
| subjects | Blood cholesterol Chronic kidney failure Development and progression Lipoprotein A Low density lipoproteins Medical research Medicine, Experimental Physiological aspects Trans fatty acids Triglycerides |
| title | LIPID ABNORMALITIES, LIPOPROTEIN AND APOPROTEIN PATTERN IN NON-DIALYZED PATIENTS WITH CHRONIC KIDNEY DISEASE |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T19%3A29%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=LIPID%20ABNORMALITIES,%20LIPOPROTEIN%20AND%20APOPROTEIN%20PATTERN%20IN%20NON-DIALYZED%20PATIENTS%20WITH%20CHRONIC%20KIDNEY%20DISEASE&rft.jtitle=Indian%20journal%20of%20clinical%20biochemistry&rft.au=Rao,%20A.M&rft.date=2022-05-24&rft.volume=25&rft.issue=1&rft.spage=47&rft.pages=47-&rft.issn=0970-1915&rft_id=info:doi/&rft_dat=%3Cgale%3EA734897317%3C/gale%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_galeid=A734897317&rfr_iscdi=true |