Clinical performance of an antibody-free assay for plasma A[beta]42/A[beta]40 to detect early alterations of Alzheimer's disease in individuals with subjective cognitive decline

Background Accessible and cost-effective diagnostic tools are urgently needed to accurately quantify blood biomarkers to support early diagnosis of Alzheimer's disease (AD). In this study, we investigated the ability of plasma amyloid-beta (A[beta])42/A[beta]40 ratio measured by an antibody-fre...

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Veröffentlicht in:	Alzheimer's research & therapy 2023-01, Vol.15 (1)
Hauptverfasser:	Pascual-Lucas, María, Allué, José Antonio, Sarasa, Leticia, Fandos, Noelia, Castillo, Sergio, Terencio, Jose, Sarasa, Manuel, Tartari, Juan Pablo, Sanabria, Ãngela, Tárraga, Lluís, Ruíz, Agustín, Marquié, Marta, Seo, Sang Won, Jang, Hyemin, Boada, Mercè, Aguilera, N, Alarcón-Martín, E, Alegret, M, Alonso-Lana, S, Berthier, M, Bojayrin, U, Buendia, M, Bullich, S, Campos, F, Cano, A, Caéabate, P, Caéada, L, Cuevas, C, de Rojas, I, Diego, S, Espinosa, A, Esteban-De Antonio, E, Gailhajenet, A, García-Sánchez, A, García, P, Giménez, J, Gómez-Chiari, M, Guitart, M, Hernández, I, Ibarria, M, Lafuente, A, Lleonart, N, Lomeéa, F, Martín, E, Moreno, M, Morera, A, Montrreal, L, Muéoz, N, Narvaiza, L, Niéerola, A, Nogales, A. B, Núéez, L, Orellana, A, Ortega, G, Páez, A, Pancho, A, Pelejà, E, Pérez, E, Pérez-Cordon, A, Perissinotti, A, Preckler, S, Pytel, V, Ricciardi, M, Rodríguez-Gomez, O, Roé-Vellvé, N, Ramis, M. I, Rosende-Roca, M, Seguer, S, Sotolongo-Grau, O, Stephens, A, Tejero, M. A, Torres, M, Valero, S, Vargas, L, Vivas, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Amyloid beta-protein Blood Development and progression Diagnosis Health aspects Mass spectrometry Measurement Medical examination Methods
Online-Zugang:	Volltext
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