CDK8/19 inhibition plays an important role in pancreatic [beta]-cell induction from human iPSCs

Background Transplantation of differentiated cells from human-induced pluripotent stem cells (hiPSCs) holds great promise for clinical treatments. Eliminating the risk factor of malignant cell transformation is essential for ensuring the safety of such cells. This study was aimed at assessing and mi...

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Veröffentlicht in:Stem cell research & therapy 2023-01, Vol.14 (1)
Hauptverfasser: Sakuma, Kensuke, Tsubooka-Yamazoe, Noriko, Hashimoto, Kiyohiro, Sakai, Nozomu, Asano, Shinya, Watanabe-Matsumoto, Saori, Watanabe, Takeshi, Saito, Bunnai, Matsumoto, Hirokazu, Ueno, Hikaru, Ito, Ryo, Toyoda, Taro
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Sprache:eng
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