Intestinal occlusion due to Burkitt lymphoma: an unusual cause
We present the case of a 37-year-old Caucasian woman, with no history of interest, who came to the emergency room for an occlusive condition of 24 hours' evolution. The patient reported a weight loss of 12 kg in the last month, as well as the appearance of a lump in the left breast in the last...
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Veröffentlicht in: | Revista española de enfermedades digestivas 2022-11, Vol.114 (11), p.692 |
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creator | Sierra Gabarda, Olivia Aguirre Portu, Nerea Casas Deza, Diego Lamuela Calvo, Luis Javier Betoré Glaría, Elena Julián Gomara, Belén Abecia Martínez, Emilio Ignacio Fernández Bonilla, Eva María |
description | We present the case of a 37-year-old Caucasian woman, with no history of interest, who came to the emergency room for an occlusive condition of 24 hours' evolution. The patient reported a weight loss of 12 kg in the last month, as well as the appearance of a lump in the left breast in the last week. A chest-abdominal CT scan revealed multiple solid-appearing nodules in the left breast, a metastatic liver lesion, and a tumor-like mass in the right iliac fossa measuring 90x60 mm. A biopsy of the breast lesion revealed a diffuse architectural pattern with destruction of the parenchyma and irregular medium-large cellularity with intense and diffuse expression of CD20, CD10 and Bcl6 and a proliferative index of practically 100%, consistent with lymphoma. Burkitt stage IV. Intestinal obstruction constitutes about 15% of hospital admissions for abdominal pain, representing a significant cause of hospital mortality. Although the most common causes of small bowel obstruction are benign (adhesions, hernias), intraluminal lesions such as inflammatory bowel disease or neoplasms are well-established causes associated with this clinical picture. Lymphomas constitute 25% of cases of intestinal obstruction of neoplastic origin; among them, Burkitt lymphoma is a rare type of B-cell lymphoma characterized by rapid and aggressive cell growth, the most common initial involvement of which is located at the abdominal and extra-nodal level. |
doi_str_mv | 10.17235/reed.2022.8765/2022 |
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The patient reported a weight loss of 12 kg in the last month, as well as the appearance of a lump in the left breast in the last week. A chest-abdominal CT scan revealed multiple solid-appearing nodules in the left breast, a metastatic liver lesion, and a tumor-like mass in the right iliac fossa measuring 90x60 mm. A biopsy of the breast lesion revealed a diffuse architectural pattern with destruction of the parenchyma and irregular medium-large cellularity with intense and diffuse expression of CD20, CD10 and Bcl6 and a proliferative index of practically 100%, consistent with lymphoma. Burkitt stage IV. Intestinal obstruction constitutes about 15% of hospital admissions for abdominal pain, representing a significant cause of hospital mortality. Although the most common causes of small bowel obstruction are benign (adhesions, hernias), intraluminal lesions such as inflammatory bowel disease or neoplasms are well-established causes associated with this clinical picture. Lymphomas constitute 25% of cases of intestinal obstruction of neoplastic origin; among them, Burkitt lymphoma is a rare type of B-cell lymphoma characterized by rapid and aggressive cell growth, the most common initial involvement of which is located at the abdominal and extra-nodal level.</description><identifier>ISSN: 1130-0108</identifier><identifier>DOI: 10.17235/reed.2022.8765/2022</identifier><identifier>PMID: 35607925</identifier><language>eng</language><publisher>Spain: Sociedad Espanola de Patologia Digestivas</publisher><subject>Abdominal Pain - etiology ; Adult ; Burkitt Lymphoma - complications ; Burkitt Lymphoma - diagnostic imaging ; Female ; Humans ; Intestinal Obstruction - diagnostic imaging ; Intestinal Obstruction - etiology ; Lymphoma, B-Cell - pathology</subject><ispartof>Revista española de enfermedades digestivas, 2022-11, Vol.114 (11), p.692</ispartof><rights>COPYRIGHT 2022 Sociedad Espanola de Patologia Digestivas</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c387t-3f93c55bd41493585f57442a90e43670b0ea35830cb5544e3c4096d420123db93</citedby><cites>FETCH-LOGICAL-c387t-3f93c55bd41493585f57442a90e43670b0ea35830cb5544e3c4096d420123db93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,860,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35607925$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sierra Gabarda, Olivia</creatorcontrib><creatorcontrib>Aguirre Portu, Nerea</creatorcontrib><creatorcontrib>Casas Deza, Diego</creatorcontrib><creatorcontrib>Lamuela Calvo, Luis Javier</creatorcontrib><creatorcontrib>Betoré Glaría, Elena</creatorcontrib><creatorcontrib>Julián Gomara, Belén</creatorcontrib><creatorcontrib>Abecia Martínez, Emilio Ignacio</creatorcontrib><creatorcontrib>Fernández Bonilla, Eva María</creatorcontrib><title>Intestinal occlusion due to Burkitt lymphoma: an unusual cause</title><title>Revista española de enfermedades digestivas</title><addtitle>Rev Esp Enferm Dig</addtitle><description>We present the case of a 37-year-old Caucasian woman, with no history of interest, who came to the emergency room for an occlusive condition of 24 hours' evolution. The patient reported a weight loss of 12 kg in the last month, as well as the appearance of a lump in the left breast in the last week. A chest-abdominal CT scan revealed multiple solid-appearing nodules in the left breast, a metastatic liver lesion, and a tumor-like mass in the right iliac fossa measuring 90x60 mm. A biopsy of the breast lesion revealed a diffuse architectural pattern with destruction of the parenchyma and irregular medium-large cellularity with intense and diffuse expression of CD20, CD10 and Bcl6 and a proliferative index of practically 100%, consistent with lymphoma. Burkitt stage IV. Intestinal obstruction constitutes about 15% of hospital admissions for abdominal pain, representing a significant cause of hospital mortality. Although the most common causes of small bowel obstruction are benign (adhesions, hernias), intraluminal lesions such as inflammatory bowel disease or neoplasms are well-established causes associated with this clinical picture. Lymphomas constitute 25% of cases of intestinal obstruction of neoplastic origin; among them, Burkitt lymphoma is a rare type of B-cell lymphoma characterized by rapid and aggressive cell growth, the most common initial involvement of which is located at the abdominal and extra-nodal level.</description><subject>Abdominal Pain - etiology</subject><subject>Adult</subject><subject>Burkitt Lymphoma - complications</subject><subject>Burkitt Lymphoma - diagnostic imaging</subject><subject>Female</subject><subject>Humans</subject><subject>Intestinal Obstruction - diagnostic imaging</subject><subject>Intestinal Obstruction - etiology</subject><subject>Lymphoma, B-Cell - pathology</subject><issn>1130-0108</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkMtOwzAQRb0A0VL4A4QisU46fsUJC6RS8ahUiQ2sLcdxwJBHFdsL_h6npQsk5IVHM_eMRgehKwwZFoTy5WhMnREgJCtEzpdTdYLmGFNIAUMxQ-fOfQIwmnNyhmaU5yBKwufobtN747ztVZsMWrfB2aFP6mASPyT3Yfyy3iftd7f7GDp1m6g-CX1wIaa1Cs5coNNGtc5c_v4L9Pb48Lp-TrcvT5v1aptqWgif0qakmvOqZpiVlBe84YIxokow8SQBFRgV2xR0xTljhmoGZV4zApjQuirpAt0c9r6r1kjbN4Mfle6s03IlSCl4LjCNqeyfVHy16aweetPY2P8DsAOgx8G50TRyN9pOjd8Sg9yblZNZOfmUk9l9FbHrA7YLVRfHR-iolf4Au7V0ag</recordid><startdate>202211</startdate><enddate>202211</enddate><creator>Sierra Gabarda, Olivia</creator><creator>Aguirre Portu, Nerea</creator><creator>Casas Deza, Diego</creator><creator>Lamuela Calvo, Luis Javier</creator><creator>Betoré Glaría, Elena</creator><creator>Julián Gomara, Belén</creator><creator>Abecia Martínez, Emilio Ignacio</creator><creator>Fernández Bonilla, Eva María</creator><general>Sociedad Espanola de Patologia Digestivas</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>INF</scope></search><sort><creationdate>202211</creationdate><title>Intestinal occlusion due to Burkitt lymphoma: an unusual cause</title><author>Sierra Gabarda, Olivia ; Aguirre Portu, Nerea ; Casas Deza, Diego ; Lamuela Calvo, Luis Javier ; Betoré Glaría, Elena ; Julián Gomara, Belén ; Abecia Martínez, Emilio Ignacio ; Fernández Bonilla, Eva María</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c387t-3f93c55bd41493585f57442a90e43670b0ea35830cb5544e3c4096d420123db93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Abdominal Pain - etiology</topic><topic>Adult</topic><topic>Burkitt Lymphoma - complications</topic><topic>Burkitt Lymphoma - diagnostic imaging</topic><topic>Female</topic><topic>Humans</topic><topic>Intestinal Obstruction - diagnostic imaging</topic><topic>Intestinal Obstruction - etiology</topic><topic>Lymphoma, B-Cell - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sierra Gabarda, Olivia</creatorcontrib><creatorcontrib>Aguirre Portu, Nerea</creatorcontrib><creatorcontrib>Casas Deza, Diego</creatorcontrib><creatorcontrib>Lamuela Calvo, Luis Javier</creatorcontrib><creatorcontrib>Betoré Glaría, Elena</creatorcontrib><creatorcontrib>Julián Gomara, Belén</creatorcontrib><creatorcontrib>Abecia Martínez, Emilio Ignacio</creatorcontrib><creatorcontrib>Fernández Bonilla, Eva María</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale OneFile: Informe Academico</collection><jtitle>Revista española de enfermedades digestivas</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sierra Gabarda, Olivia</au><au>Aguirre Portu, Nerea</au><au>Casas Deza, Diego</au><au>Lamuela Calvo, Luis Javier</au><au>Betoré Glaría, Elena</au><au>Julián Gomara, Belén</au><au>Abecia Martínez, Emilio Ignacio</au><au>Fernández Bonilla, Eva María</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intestinal occlusion due to Burkitt lymphoma: an unusual cause</atitle><jtitle>Revista española de enfermedades digestivas</jtitle><addtitle>Rev Esp Enferm Dig</addtitle><date>2022-11</date><risdate>2022</risdate><volume>114</volume><issue>11</issue><spage>692</spage><pages>692-</pages><issn>1130-0108</issn><abstract>We present the case of a 37-year-old Caucasian woman, with no history of interest, who came to the emergency room for an occlusive condition of 24 hours' evolution. The patient reported a weight loss of 12 kg in the last month, as well as the appearance of a lump in the left breast in the last week. A chest-abdominal CT scan revealed multiple solid-appearing nodules in the left breast, a metastatic liver lesion, and a tumor-like mass in the right iliac fossa measuring 90x60 mm. A biopsy of the breast lesion revealed a diffuse architectural pattern with destruction of the parenchyma and irregular medium-large cellularity with intense and diffuse expression of CD20, CD10 and Bcl6 and a proliferative index of practically 100%, consistent with lymphoma. Burkitt stage IV. Intestinal obstruction constitutes about 15% of hospital admissions for abdominal pain, representing a significant cause of hospital mortality. Although the most common causes of small bowel obstruction are benign (adhesions, hernias), intraluminal lesions such as inflammatory bowel disease or neoplasms are well-established causes associated with this clinical picture. Lymphomas constitute 25% of cases of intestinal obstruction of neoplastic origin; among them, Burkitt lymphoma is a rare type of B-cell lymphoma characterized by rapid and aggressive cell growth, the most common initial involvement of which is located at the abdominal and extra-nodal level.</abstract><cop>Spain</cop><pub>Sociedad Espanola de Patologia Digestivas</pub><pmid>35607925</pmid><doi>10.17235/reed.2022.8765/2022</doi><oa>free_for_read</oa></addata></record> |
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subjects | Abdominal Pain - etiology Adult Burkitt Lymphoma - complications Burkitt Lymphoma - diagnostic imaging Female Humans Intestinal Obstruction - diagnostic imaging Intestinal Obstruction - etiology Lymphoma, B-Cell - pathology |
title | Intestinal occlusion due to Burkitt lymphoma: an unusual cause |
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