T-lymphocyte-derived enkephalins reduce T.sub.h1/T.sub.h17 colitis and associated pain in mice

Background Endogenous opioids, including enkephalins, are fundamental regulators of pain. In inflammatory conditions, the local release of opioids by leukocytes at the inflammatory site inhibits nociceptor firing, thereby inducing analgesia. Accordingly, in chronic intestinal T.sub.h1/T.sub.h17-asso...

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Veröffentlicht in:	Journal of gastroenterology 2018-02, Vol.53 (2), p.215
Hauptverfasser:	Basso, Lilian, Garnier, Laure, Bessac, Arnaud, Boué, Jérôme, Blanpied, Catherine, Cenac, Nicolas, Laffont, Sophie
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Care and treatment Colitis Enkephalins Inflammation Opioids Pain T cells
Online-Zugang:	Volltext
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