Knockdown of FAM64A suppresses proliferation and migration of breast cancer cells

Background FAM64A is a mitotic regulator promoting cell metaphase–anaphase transition, and it is frequently reported to be highly expressed in cancer cells. However, the role of FAM64A in human breast cancer (BrC) is poorly studied. Methods The expression of FAM64A mRNA in BrC samples was determined...

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Veröffentlicht in:	Breast cancer (Tokyo, Japan) Japan), 2019-11, Vol.26 (6), p.835-845
Hauptverfasser:	Yao, Zhuocheng, Zheng, Xianchong, Lu, Sitong, He, Zhanxin, Miao, Yutian, Huang, Hehai, Chu, Xinwei, Cai, Chunqing, Zou, Fei
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Antigens, CD - metabolism Breast cancer Breast Neoplasms - metabolism Breast Neoplasms - pathology Cadherins - metabolism Cancer cells Cancer Research Cell Movement - genetics Cell Proliferation - genetics DNA binding proteins Epithelial-Mesenchymal Transition - genetics Female G1 Phase Cell Cycle Checkpoints - genetics Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Humans Intracellular Signaling Peptides and Proteins - genetics Intracellular Signaling Peptides and Proteins - metabolism Kaplan-Meier Estimate MCF-7 Cells Medicine Medicine & Public Health Nuclear Proteins - genetics Nuclear Proteins - metabolism Oncology Original Article Prognosis RNA RNA Interference Snail Family Transcription Factors - metabolism Surgery Surgical Oncology Transfection Twist-Related Protein 1 - metabolism Vimentin - metabolism
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