Endophenotypes as a measure of suicidality

Suicide is thought to result from the harmful interaction of multiple factors that have social, environmental, neurobiological, and genetic backgrounds. Recent studies have suggested that genetic predisposition to suicidal behavior may be independent of the risk of suicide associated to mental disor...

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Veröffentlicht in:	Journal of applied genetics 2012-11, Vol.53 (4), p.389-413
Hauptverfasser:	Chistiakov, Dimitry A., Kekelidze, Zurab I., Chekhonin, Vladimir P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcoholism Alleles Animal Genetics and Genomics Biomedical and Life Sciences Brain - metabolism Brain - pathology Depressive Disorder, Major - diagnosis Endophenotypes - analysis Endophenotypes - metabolism Epigenesis, Genetic Genetic aspects Genetic Association Studies Genetic polymorphisms Genetic Predisposition to Disease Human Genetics Human Genetics • Review Humans Hydroxyindoleacetic Acid - cerebrospinal fluid Impulsive Behavior - genetics Impulsive Behavior - psychology Life Sciences Microbial Genetics and Genomics Neurophysiology Plant Genetics and Genomics Polymorphism, Genetic Risk Factors Serotonin Plasma Membrane Transport Proteins - genetics Serotonin Plasma Membrane Transport Proteins - metabolism Suicidal behavior Suicide Suicide - psychology Tryptophan Hydroxylase - genetics Tryptophan Hydroxylase - metabolism
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