Epithelial-derived exosomes promote M2 macrophage polarization via Notch2/SOCSl during mechanical ventilation

Alveolar macrophages (AMs) play an essential role in ventilator-induced lung injury (VILI). Exosomes and their cargo, including microRNAs (miRNAs/miRs) serve as regulators of the intercellular communications between macrophages and epithelial cells (ECs), and are involved in maintaining homeostasis...

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Veröffentlicht in:International journal of molecular medicine 2022-07, Vol.50 (1), p.1
Hauptverfasser: Wang, Yanting, Xie, Wanli, Feng, Yiqi, Xu, Zhenzhen, He, Yuyao, Xiong, Yue, Chen, Lu, Li, Xia, Liu, Jie, Liu, Guoyang, Wu, Qingping
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Sprache:eng
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