Efficacy and safety of FOLFIRI/aflibercept after failure of an oxaliplatin-based regimen

Background The VELOUR study showed the benefit of FOLFIRI-Aflibercept (FA) versus FOLFIRI in patients with metastatic colorectal cancer (mCRC) in second-line treatment. However, only 36% of the included patients were [greater than or equal to]65 years. Thus, we seek to evaluate the efficacy and safe...

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Veröffentlicht in:	PloS one 2022-06, Vol.17 (6), p.e0269399
Hauptverfasser:	Martínez-Lago, Nieves, Cameselle García, Soledad, Alonso de Castro, Beatriz, Gómez-Randulfe Rodríguez, Martín I, Carmona Campos, Marta, González Villarroel, Paula, Salgado Fernández, Mercedes, De la Cámara Gómez, Juan C, Romero Reinoso, Carlos, Cousillas Castiñeiras, Antía, Méndez Méndez, José Carlos, Vidal Insua, Yolanda, Fernández-Montes, Ana
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged patients Chemotherapy, Combination Colorectal cancer Drug therapy Fluorouracil Leucovorin Metastasis Patient outcomes
Online-Zugang:	Volltext
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