Molecular Dynamics Simulation and Essential Dynamics of Deleterious Proline 12 Alanine Single-Nucleotide Polymorphism in PPAR γ 2 Associated with Type 2 Diabetes, Cardiovascular Disease, and Nonalcoholic Fatty Liver Disease

. Peroxisome proliferator-activated receptor- ( ) gene is located at 3p25 position. PPAR functions as the master regulator of glucose homeostasis and lipoprotein metabolism, and recent studies have reported that it is involved in various metabolic diseases such as diabetes mellitus, hyperlipidemia,...

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Veröffentlicht in:	PPAR research 2022-05, Vol.2022, p.3833668
Hauptverfasser:	Taghvaei, Somayye, Saremi, Leila
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissues Coronary heart disease Diabetes therapy Fatty liver Glucose metabolism Hydrogen bonding Molecular dynamics Physiological aspects Proline Single nucleotide polymorphisms Type 2 diabetes
Online-Zugang:	Volltext
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