Effects of liquid extract from Plinia cauliflora fruits residues on Chinese hamsters biochemical parameters/ Efeitos do extrato liquido de residuos de frutos de Plinia cauliflora sobre os parametros bioquimicos de hamsters chineses
Plinia cauliflora (Mart.) Kausel, popularly known as jabuticaba, is rich in polyphenols. Phenolic compounds exhibit several biological properties, which reflect on biomarkers such as biochemical parameters. In the present study, we evaluated the plasmatic levels of glucose, total cholesterol, HDL-ch...
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Veröffentlicht in: | Brazilian journal of biology 2023-01, Vol.83 |
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container_title | Brazilian journal of biology |
container_volume | 83 |
creator | Borges, Leonardo Luiz Martins, Frederico Severino Franco, Joao Jose Bailao, Elisa Flavia Luiz Cardoso de Melo Cruvinel, Wilson Uyemura, Sergio Akira da Conceicao, Edemilson Cardoso |
description | Plinia cauliflora (Mart.) Kausel, popularly known as jabuticaba, is rich in polyphenols. Phenolic compounds exhibit several biological properties, which reflect on biomarkers such as biochemical parameters. In the present study, we evaluated the plasmatic levels of glucose, total cholesterol, HDL-cholesterol, triglycerides, and uric acid of Chinese hamsters fed for 45 days with a regular diet or cholesterol-enriched diet supplemented with a liquid extract obtained from P. cauliflora fruits residues standardized in ellagic acid and total phenolic compounds. The results showed that the concentrated extract obtained from jabuticaba residues increased the glycemia of animals fed with a regular diet and reduced the plasmatic uric acid levels of animals fed with a cholesterol-enriched diet. Since hyperuricemia is considered to be a significant risk factor of metabolic disorders and the principal pathological basis of gout, the liquid extract from P. cauliflora fruits residues would be a promising candidate as a novel hypouricaemic agent for further investigation. |
doi_str_mv | 10.1590/1519-6984.242439 |
format | Article |
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Kausel, popularly known as jabuticaba, is rich in polyphenols. Phenolic compounds exhibit several biological properties, which reflect on biomarkers such as biochemical parameters. In the present study, we evaluated the plasmatic levels of glucose, total cholesterol, HDL-cholesterol, triglycerides, and uric acid of Chinese hamsters fed for 45 days with a regular diet or cholesterol-enriched diet supplemented with a liquid extract obtained from P. cauliflora fruits residues standardized in ellagic acid and total phenolic compounds. The results showed that the concentrated extract obtained from jabuticaba residues increased the glycemia of animals fed with a regular diet and reduced the plasmatic uric acid levels of animals fed with a cholesterol-enriched diet. Since hyperuricemia is considered to be a significant risk factor of metabolic disorders and the principal pathological basis of gout, the liquid extract from P. cauliflora fruits residues would be a promising candidate as a novel hypouricaemic agent for further investigation.</description><identifier>ISSN: 1519-6984</identifier><identifier>EISSN: 1678-4375</identifier><identifier>DOI: 10.1590/1519-6984.242439</identifier><language>eng</language><publisher>Association of the Brazilian Journal of Biology</publisher><ispartof>Brazilian journal of biology, 2023-01, Vol.83</ispartof><rights>COPYRIGHT 2023 Association of the Brazilian Journal of Biology</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,782,786,866,27931,27932</link.rule.ids></links><search><creatorcontrib>Borges, Leonardo Luiz</creatorcontrib><creatorcontrib>Martins, Frederico Severino</creatorcontrib><creatorcontrib>Franco, Joao Jose</creatorcontrib><creatorcontrib>Bailao, Elisa Flavia Luiz Cardoso</creatorcontrib><creatorcontrib>de Melo Cruvinel, Wilson</creatorcontrib><creatorcontrib>Uyemura, Sergio Akira</creatorcontrib><creatorcontrib>da Conceicao, Edemilson Cardoso</creatorcontrib><title>Effects of liquid extract from Plinia cauliflora fruits residues on Chinese hamsters biochemical parameters/ Efeitos do extrato liquido de residuos de frutos de Plinia cauliflora sobre os parametros bioquimicos de hamsters chineses</title><title>Brazilian journal of biology</title><description>Plinia cauliflora (Mart.) Kausel, popularly known as jabuticaba, is rich in polyphenols. Phenolic compounds exhibit several biological properties, which reflect on biomarkers such as biochemical parameters. In the present study, we evaluated the plasmatic levels of glucose, total cholesterol, HDL-cholesterol, triglycerides, and uric acid of Chinese hamsters fed for 45 days with a regular diet or cholesterol-enriched diet supplemented with a liquid extract obtained from P. cauliflora fruits residues standardized in ellagic acid and total phenolic compounds. The results showed that the concentrated extract obtained from jabuticaba residues increased the glycemia of animals fed with a regular diet and reduced the plasmatic uric acid levels of animals fed with a cholesterol-enriched diet. 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Kausel, popularly known as jabuticaba, is rich in polyphenols. Phenolic compounds exhibit several biological properties, which reflect on biomarkers such as biochemical parameters. In the present study, we evaluated the plasmatic levels of glucose, total cholesterol, HDL-cholesterol, triglycerides, and uric acid of Chinese hamsters fed for 45 days with a regular diet or cholesterol-enriched diet supplemented with a liquid extract obtained from P. cauliflora fruits residues standardized in ellagic acid and total phenolic compounds. The results showed that the concentrated extract obtained from jabuticaba residues increased the glycemia of animals fed with a regular diet and reduced the plasmatic uric acid levels of animals fed with a cholesterol-enriched diet. Since hyperuricemia is considered to be a significant risk factor of metabolic disorders and the principal pathological basis of gout, the liquid extract from P. cauliflora fruits residues would be a promising candidate as a novel hypouricaemic agent for further investigation.</abstract><pub>Association of the Brazilian Journal of Biology</pub><doi>10.1590/1519-6984.242439</doi></addata></record> |
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title | Effects of liquid extract from Plinia cauliflora fruits residues on Chinese hamsters biochemical parameters/ Efeitos do extrato liquido de residuos de frutos de Plinia cauliflora sobre os parametros bioquimicos de hamsters chineses |
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