Effect of a single dose of 8 mg moxidectin or 150 [mu]g/kg ivermectin on O. volvulus skin microfilariae in a randomized trial: Differences between areas in the Democratic Republic of the Congo, Liberia and Ghana and impact of intensity of infection

Background Our study in CDTI-naïve areas in Nord Kivu and Ituri (Democratic Republic of the Congo, DRC), Lofa County (Liberia) and Nkwanta district (Ghana) showed that a single 8 mg moxidectin dose reduced skin microfilariae density (microfilariae/mg skin, SmfD) better and for longer than a single 1...

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Veröffentlicht in:PLoS neglected tropical diseases 2022-04, Vol.16 (4)
Hauptverfasser: Bakajika, Didier, Kanza, Eric M, Opoku, Nicholas O, Howard, Hayford M, Mambandu, Germain L, Nyathirombo, Amos, Nigo, Maurice M, Kennedy, Kambale Kasonia, Masembe, Safari L, Mumbere, Mupenzi, Kataliko, Kambale, Bolay, Kpehe M, Attah, Simon K, Olipoh, George, Asare, Sampson, Vaillant, Michel, Halleux, Christine M, Kuesel, Annette C
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Sprache:eng
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