Periorbital lupus erythematosus profundus: A case report and review of the literature/Periorbital lupus eritematozus profundus: Bir olgu sunumu ve literaturun gozden gecirilmesi

Lupus erythematosus profundus (LEP), is a rare form of, chronic cutaneous LE, also called lupus erythematosus panniculitis. LEP is characterized by subcutaneous fatty tissue involvement specifically in patients with LE. Before systemic LE was diagnosed, very few reports reported the presence of lesions of lupus erythematosus profundus. The rare manifestations of the disease are remarkable with the unusual features of the cases. A 43-year-old female patient diagnosed with bilateral periorbital LEP was presented and the literature was reviewed. Significant clinical improvement was achieved in the patient who was given systemic hydroxychloroquine and topical pimecrolimus therapy. This report suggests that asymptomatic periorbital erythema and edema may develop as a manifestation of LEP Keywords: Lupus erythematosus, lupus erythematosus profundus, lupus panniculitis, orbital area Lupus eritematozus profundus (LEP), nadir gorulen bir kronik kutanoz lupus eritematozus turu olup, lupus eritematozus pannikuliti olarak da adlandirilmaktadir. LEP, LE hastalarinda spesifik olarak subkutan yag doku tutulumu ile karakterizedir. Sistemik lupus eritematozus tanisi konulmadan once LEP lezyonlarinin varligini bildiren cok az sayida rapor bildirilmistir. Hastaligin nadir gorulen bulgulari, olgularin sira disi ozellikleri ile dikkat cekici olmaktadir. Burada bilateral periorbital LEP tanisi konulan, 43 yasinda bir kadin olgu sunulmus ve literatur gozden gecirilmistir. Sistemik hidroksiklorokin ve topikal pimekrolimus tedavisi verilen hastada anlamli klinik iyilesme saglanmistir. Bu rapor, asemptomatik periorbital eritem ve odemin LEP'nin bir bulgusu olarak gelisebilecegini desteklemektedir. Anahtar Kelimeler: Lupus eritematozus, lupus eritematozus profundus, lupus pannikuliti, orbital alan