Modulation of Sirtl-mTORCI Pathway in Microglia Attenuates Retinal Ganglion Cell Loss After Optic Nerve Injury

Purpose: Optic nerve injury (ONI) causes neuroinflammation and neurodegeneration leading to visual deficits. The response of microglia has emerged as an impactful component of etiology in neurodegeneration. This study aimed to investigate the effect of SIRT1-mTORC1 signaling pathway in microglia reg...

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Veröffentlicht in:	Journal of inflammation research 2021-12, Vol.14, p.6857
Hauptverfasser:	Mou, Qianxue, Yao, Ke, Ye, Meng, Zhao, Bowen, Hu, Yuanyuan, Lou, Xiaotong, Li, Huixia, Zhang, Hong, Zhao, Yin
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Ganglion Protein binding
Online-Zugang:	Volltext
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