Inhibition of matrix stiffness relating integrin [beta]1 signaling pathway inhibits tumor growth in vitro and in hepatocellular cancer xenografts

Background Cancer development is strictly correlated to composition and physical properties of the extracellular matrix. Particularly, a higher matrix stiffness has been demonstrated to promote tumor sustained growth. Our purpose was to explore the role of matrix stiffness in liver cancer developmen...

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Veröffentlicht in:	BMC cancer 2021-11, Vol.21 (1)
Hauptverfasser:	Wang, Changsong, Jiang, Xiaozhong, Huang, Bin, Zhou, Wenhao, Cui, Xiao, Zheng, Chenghong, Liu, Fenghao, Bi, Jieling, Zhang, Yi, Luo, Hong, Yuan, Lin, Yang, Jianyong, Yu, Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Development and progression Extracellular matrix Health aspects Hepatoma Integrins Physiological aspects
Online-Zugang:	Volltext
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