FOXA1 Suppresses SATB1 Transcription and Inactivates the Wnt/[beta]-Catenin Pathway to Alleviate Diabetic Nephropathy in a Mouse Model

Objective: Diabetic nephropathy (DN) represents the most common diabetic complication that may lead to end-stage renal disease. This work focused on the effect of FOXA1 on the DN development and the molecular mechanism. Methods: A mouse model of DN was induced by high-fat diets and streptozotocin. T...

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Veröffentlicht in:	Diabetes, metabolic syndrome and obesity metabolic syndrome and obesity, 2021-09, Vol.14, p.3975
Hauptverfasser:	Zhu, Hong, Peng, Jiarui, Li, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Blood sugar Chronic kidney failure Diabetic nephropathies Genetic transcription Scientific equipment and supplies industry Streptozocin Type 2 diabetes
Online-Zugang:	Volltext
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