Delivery room oxygen physiology and respiratory interventions for newborns with cyanotic congenital heart disease

Objective To characterize pulse oxygen saturation (SpO 2 ) trajectories and respiratory interventions after birth for newborns with cyanotic congenital heart disease (CCHD). Study design Retrospective single-site study of newborns ≥32 weeks gestation with CCHD: single ventricle with critical aortic...

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Veröffentlicht in:Journal of perinatology 2021-09, Vol.41 (9), p.2309-2316
Hauptverfasser: Thomas, Alyssa R., Ma, Amy L., Weinberg, Danielle D., Huber, Matthew, Ades, Anne, Rychik, Jack, Foglia, Elizabeth E.
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Sprache:eng
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Zusammenfassung:Objective To characterize pulse oxygen saturation (SpO 2 ) trajectories and respiratory interventions after birth for newborns with cyanotic congenital heart disease (CCHD). Study design Retrospective single-site study of newborns ≥32 weeks gestation with CCHD: single ventricle with critical aortic obstruction (SV-CAO), critical pulmonic obstruction (CPO), transposition of the great arteries (TGA). Minute-to-minute SpO 2 values and respiratory interventions were summarized and compared. Results Two hundred infants were enrolled. SpO 2 at each minute differed across groups ( p  
ISSN:0743-8346
1476-5543
DOI:10.1038/s41372-021-01029-2