ENDOVASCULAR REVASCULARIZATION OF CAROTID ARTERY STENOSIS /ENDOVASKULARNA REVASKULARIZACIJA SUZENJA KAROTIDNE ARTERIJE

Introduction. Endovascular revascularization is a peripheral artery disease therapy used to improve blood flow in blood vessels. The objective of this study was to analyze the types and prevalence of comorbidities in patients with indications for carotid artery revascularization, as well as early re...

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Veröffentlicht in:Medicinski pregled 2020-11, Vol.73 (11-12), p.351
Hauptverfasser: Budinski, Slavko, Manojlovic, Vladimir, Budakov, Nebojsa, Batinic, Nikola, Budinski, Milica Pejakovic, Stojic, Marko
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container_issue 11-12
container_start_page 351
container_title Medicinski pregled
container_volume 73
creator Budinski, Slavko
Manojlovic, Vladimir
Budakov, Nebojsa
Batinic, Nikola
Budinski, Milica Pejakovic
Stojic, Marko
description Introduction. Endovascular revascularization is a peripheral artery disease therapy used to improve blood flow in blood vessels. The objective of this study was to analyze the types and prevalence of comorbidities in patients with indications for carotid artery revascularization, as well as early results of endovascular carotid artery revascularization in relation to periprocedural complications. Material and Methods. This retrospective study was conducted from October 2014 to October 2019 and included 96 patients. Descriptive and comparative statistical analysis was performed in all patients, male and female, and those with both symptomatic and asymptomatic carotid diseases. Results. The study included 96 patients, of whom 69.8% were male and 30.2% were female. A successful endovascular procedure was performed in 89.6% of patients, while in 10.4% of patients the procedure failed. The distribution of patients by sex, age and the duration of procedure, showed a statistically significant difference (p < 0.05) in the age (p = 0.0003) and duration of the procedure (p = 0.022). The comparison of two groups of patients, with symptomatic and asymptomatic carotid atherosclerotic disease, hyperlipoproteinemia (p = 0.015) showed a statistically significant difference (p < 0.05) between the two groups. Conclusion. Endovascular revascularization has a high success rate in the treatment of atherosclerotic disease of the carotid arteries as well as low periprocedural morbidity and mortality. The analysis of gender-related differences, we concluded that endovascular revascularization lasts significantly longer in female patients, and that the average age is significantly higher in male patients compared to females. We also concluded that hyperlipoproteinemia is a major risk factor for carotid artery disease. Key words: Carotid Stenosis; Stroke; Cerebral Revascularization; Endovascular Procedures; Treatment Outcome; Stents; Atherosclerosis; Minimally Invasive Surgical Procedures: Risk Factors; Comorbidity Uvod. Endovaskularna revaskularizacija podrazumeva rekonstrukciju obolelog krvnog suda metodama koje se koriste da poboljsaju protok krvi kroz krvni sud. Cilj rada bila je analiza komorbiditeta po tipu i ucestalosti javljanja kod pacijenata sa indikacijom za revaskularizaciju karotidnih arterija, kao i analiza ranih rezultata endovaskularne revaskularizacije karotidnih arterija u odnosu na periproceduralne komplikacije. Materijal i metode. Retrospektivna studija izmedu
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Endovascular revascularization is a peripheral artery disease therapy used to improve blood flow in blood vessels. The objective of this study was to analyze the types and prevalence of comorbidities in patients with indications for carotid artery revascularization, as well as early results of endovascular carotid artery revascularization in relation to periprocedural complications. Material and Methods. This retrospective study was conducted from October 2014 to October 2019 and included 96 patients. Descriptive and comparative statistical analysis was performed in all patients, male and female, and those with both symptomatic and asymptomatic carotid diseases. Results. The study included 96 patients, of whom 69.8% were male and 30.2% were female. A successful endovascular procedure was performed in 89.6% of patients, while in 10.4% of patients the procedure failed. The distribution of patients by sex, age and the duration of procedure, showed a statistically significant difference (p &lt; 0.05) in the age (p = 0.0003) and duration of the procedure (p = 0.022). The comparison of two groups of patients, with symptomatic and asymptomatic carotid atherosclerotic disease, hyperlipoproteinemia (p = 0.015) showed a statistically significant difference (p &lt; 0.05) between the two groups. Conclusion. Endovascular revascularization has a high success rate in the treatment of atherosclerotic disease of the carotid arteries as well as low periprocedural morbidity and mortality. The analysis of gender-related differences, we concluded that endovascular revascularization lasts significantly longer in female patients, and that the average age is significantly higher in male patients compared to females. We also concluded that hyperlipoproteinemia is a major risk factor for carotid artery disease. Key words: Carotid Stenosis; Stroke; Cerebral Revascularization; Endovascular Procedures; Treatment Outcome; Stents; Atherosclerosis; Minimally Invasive Surgical Procedures: Risk Factors; Comorbidity Uvod. Endovaskularna revaskularizacija podrazumeva rekonstrukciju obolelog krvnog suda metodama koje se koriste da poboljsaju protok krvi kroz krvni sud. Cilj rada bila je analiza komorbiditeta po tipu i ucestalosti javljanja kod pacijenata sa indikacijom za revaskularizaciju karotidnih arterija, kao i analiza ranih rezultata endovaskularne revaskularizacije karotidnih arterija u odnosu na periproceduralne komplikacije. Materijal i metode. Retrospektivna studija izmedu oktobra 2014. i oktobra 2019. godine obuhvatila je 96 pacijenata. Radena je deskriptivna i komparativna statistika za celu populaciju izmedu grupe muskog i zenskog pola i simptomatske i asimptomatske karotidne bolesti. Rezultati. Istrazivanjem je obuhvaceno 96 bolesnika, od kojih je 69,8% bilo muskog, dok je 30,2% bilo zenskog pola. Uspesno izvrsena endovaskularna procedura je uradena kod 89,6% bolesnika, dok kod 10,4% bolesnika procedura nije uspela. Poredenjem pacijenata po polu, starosti (p = 0,0003) i trajanja procedure (p = 0,022) pokazala se statisticki znacajna razlika (p &lt; 0,05). Poredenjem dve grupe pacijenata sa simptomatskom i asimptomatskom karotidnom aterosklertoskom bolescu, hiperlipoproteinemija, (p = 0,015) pokazala se takode statisticki znacajna razlika (p &lt; 0,05). Zakljucak. Endovaskularnom revaskularizacijom se postize visok uspeh lecenja aterosklerotske bolesti karotidnih arterija, pracena je malim periproceduralnim morbiditetom i mortalitetom. Analizom rezultata po polu, zakljucili smo da endovaskularna revaskularizacija znacajno duze traje kod pacijenata zenskog pola i daje prosecna starost znacajno veca kod pacijenata muskog pola u odnosu na zenski pol. Zakljucili smo i da hiperlipoproteinemija ima znacajnu ulogu u simptomatologiji karotidne bolesti, kao i daje hiperlipoproteinemija znacajan faktor rizika za bolest karotidne arterije. Kljucne reci: karotidna stenoza; mozdani udar; cerebralna revaskularizacija; endovaskularne procedure; ishod lecenja; stentovi; ateroskleroza; minimalno invazivne hirurske procedure; faktori rizika; komorbiditet</description><identifier>ISSN: 0025-8105</identifier><identifier>DOI: 10.2298/MPNS2012351B</identifier><language>eng</language><publisher>Drustvo Lekara Vojvodine</publisher><subject>Atherosclerosis ; Comorbidity ; Comparative analysis ; Health aspects ; Medical research ; Medicine, Experimental ; Mortality ; Risk factors ; Stenosis ; Stroke (Disease)</subject><ispartof>Medicinski pregled, 2020-11, Vol.73 (11-12), p.351</ispartof><rights>COPYRIGHT 2020 Drustvo Lekara Vojvodine</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27929,27930</link.rule.ids></links><search><creatorcontrib>Budinski, Slavko</creatorcontrib><creatorcontrib>Manojlovic, Vladimir</creatorcontrib><creatorcontrib>Budakov, Nebojsa</creatorcontrib><creatorcontrib>Batinic, Nikola</creatorcontrib><creatorcontrib>Budinski, Milica Pejakovic</creatorcontrib><creatorcontrib>Stojic, Marko</creatorcontrib><title>ENDOVASCULAR REVASCULARIZATION OF CAROTID ARTERY STENOSIS /ENDOVASKULARNA REVASKULARIZACIJA SUZENJA KAROTIDNE ARTERIJE</title><title>Medicinski pregled</title><description>Introduction. Endovascular revascularization is a peripheral artery disease therapy used to improve blood flow in blood vessels. The objective of this study was to analyze the types and prevalence of comorbidities in patients with indications for carotid artery revascularization, as well as early results of endovascular carotid artery revascularization in relation to periprocedural complications. Material and Methods. This retrospective study was conducted from October 2014 to October 2019 and included 96 patients. Descriptive and comparative statistical analysis was performed in all patients, male and female, and those with both symptomatic and asymptomatic carotid diseases. Results. The study included 96 patients, of whom 69.8% were male and 30.2% were female. A successful endovascular procedure was performed in 89.6% of patients, while in 10.4% of patients the procedure failed. The distribution of patients by sex, age and the duration of procedure, showed a statistically significant difference (p &lt; 0.05) in the age (p = 0.0003) and duration of the procedure (p = 0.022). The comparison of two groups of patients, with symptomatic and asymptomatic carotid atherosclerotic disease, hyperlipoproteinemia (p = 0.015) showed a statistically significant difference (p &lt; 0.05) between the two groups. Conclusion. Endovascular revascularization has a high success rate in the treatment of atherosclerotic disease of the carotid arteries as well as low periprocedural morbidity and mortality. The analysis of gender-related differences, we concluded that endovascular revascularization lasts significantly longer in female patients, and that the average age is significantly higher in male patients compared to females. We also concluded that hyperlipoproteinemia is a major risk factor for carotid artery disease. Key words: Carotid Stenosis; Stroke; Cerebral Revascularization; Endovascular Procedures; Treatment Outcome; Stents; Atherosclerosis; Minimally Invasive Surgical Procedures: Risk Factors; Comorbidity Uvod. Endovaskularna revaskularizacija podrazumeva rekonstrukciju obolelog krvnog suda metodama koje se koriste da poboljsaju protok krvi kroz krvni sud. Cilj rada bila je analiza komorbiditeta po tipu i ucestalosti javljanja kod pacijenata sa indikacijom za revaskularizaciju karotidnih arterija, kao i analiza ranih rezultata endovaskularne revaskularizacije karotidnih arterija u odnosu na periproceduralne komplikacije. Materijal i metode. Retrospektivna studija izmedu oktobra 2014. i oktobra 2019. godine obuhvatila je 96 pacijenata. Radena je deskriptivna i komparativna statistika za celu populaciju izmedu grupe muskog i zenskog pola i simptomatske i asimptomatske karotidne bolesti. Rezultati. Istrazivanjem je obuhvaceno 96 bolesnika, od kojih je 69,8% bilo muskog, dok je 30,2% bilo zenskog pola. Uspesno izvrsena endovaskularna procedura je uradena kod 89,6% bolesnika, dok kod 10,4% bolesnika procedura nije uspela. Poredenjem pacijenata po polu, starosti (p = 0,0003) i trajanja procedure (p = 0,022) pokazala se statisticki znacajna razlika (p &lt; 0,05). Poredenjem dve grupe pacijenata sa simptomatskom i asimptomatskom karotidnom aterosklertoskom bolescu, hiperlipoproteinemija, (p = 0,015) pokazala se takode statisticki znacajna razlika (p &lt; 0,05). Zakljucak. Endovaskularnom revaskularizacijom se postize visok uspeh lecenja aterosklerotske bolesti karotidnih arterija, pracena je malim periproceduralnim morbiditetom i mortalitetom. Analizom rezultata po polu, zakljucili smo da endovaskularna revaskularizacija znacajno duze traje kod pacijenata zenskog pola i daje prosecna starost znacajno veca kod pacijenata muskog pola u odnosu na zenski pol. Zakljucili smo i da hiperlipoproteinemija ima znacajnu ulogu u simptomatologiji karotidne bolesti, kao i daje hiperlipoproteinemija znacajan faktor rizika za bolest karotidne arterije. Kljucne reci: karotidna stenoza; mozdani udar; cerebralna revaskularizacija; endovaskularne procedure; ishod lecenja; stentovi; ateroskleroza; minimalno invazivne hirurske procedure; faktori rizika; komorbiditet</description><subject>Atherosclerosis</subject><subject>Comorbidity</subject><subject>Comparative analysis</subject><subject>Health aspects</subject><subject>Medical research</subject><subject>Medicine, Experimental</subject><subject>Mortality</subject><subject>Risk factors</subject><subject>Stenosis</subject><subject>Stroke (Disease)</subject><issn>0025-8105</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNptjEtLw0AUhWehYK3u_AEDrtPO-7Ec06lOWyeSpILdlMmrRPoAI_5-I6ngQu7iXA7fdwC4w2hCiFbT5xefEYQJ5fjhAowQIjxSGPErcN117wgJLJAagS_rZ8mryeL1yqQwtb-v25jcJR4mcxibNMndDJo0t-kbzHLrk8xlcHpWlz-8N4O8PMuxWxiYrTfW97kcFrwdNtzC3oDLJuy7-vacY5DPbR4_Ravk0cVmFe2ElBHFnDGutGyUVnVBpCZYBIZYGQSvqqKQmCuqFUG04pqpAgVe0qYIvJGYSUHH4H6Y3YV9vW2PzenzI5SHtiu3RggtFKJM9tTkH6q_qj605elYN23f_xG-AZ3wYEs</recordid><startdate>20201101</startdate><enddate>20201101</enddate><creator>Budinski, Slavko</creator><creator>Manojlovic, Vladimir</creator><creator>Budakov, Nebojsa</creator><creator>Batinic, Nikola</creator><creator>Budinski, Milica Pejakovic</creator><creator>Stojic, Marko</creator><general>Drustvo Lekara Vojvodine</general><scope/></search><sort><creationdate>20201101</creationdate><title>ENDOVASCULAR REVASCULARIZATION OF CAROTID ARTERY STENOSIS /ENDOVASKULARNA REVASKULARIZACIJA SUZENJA KAROTIDNE ARTERIJE</title><author>Budinski, Slavko ; Manojlovic, Vladimir ; Budakov, Nebojsa ; Batinic, Nikola ; Budinski, Milica Pejakovic ; Stojic, Marko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g677-315445897f898eb279216a404ca65ddbb7158398203d5948b0a5c3fba5f714763</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Atherosclerosis</topic><topic>Comorbidity</topic><topic>Comparative analysis</topic><topic>Health aspects</topic><topic>Medical research</topic><topic>Medicine, Experimental</topic><topic>Mortality</topic><topic>Risk factors</topic><topic>Stenosis</topic><topic>Stroke (Disease)</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Budinski, Slavko</creatorcontrib><creatorcontrib>Manojlovic, Vladimir</creatorcontrib><creatorcontrib>Budakov, Nebojsa</creatorcontrib><creatorcontrib>Batinic, Nikola</creatorcontrib><creatorcontrib>Budinski, Milica Pejakovic</creatorcontrib><creatorcontrib>Stojic, Marko</creatorcontrib><jtitle>Medicinski pregled</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Budinski, Slavko</au><au>Manojlovic, Vladimir</au><au>Budakov, Nebojsa</au><au>Batinic, Nikola</au><au>Budinski, Milica Pejakovic</au><au>Stojic, Marko</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>ENDOVASCULAR REVASCULARIZATION OF CAROTID ARTERY STENOSIS /ENDOVASKULARNA REVASKULARIZACIJA SUZENJA KAROTIDNE ARTERIJE</atitle><jtitle>Medicinski pregled</jtitle><date>2020-11-01</date><risdate>2020</risdate><volume>73</volume><issue>11-12</issue><spage>351</spage><pages>351-</pages><issn>0025-8105</issn><abstract>Introduction. Endovascular revascularization is a peripheral artery disease therapy used to improve blood flow in blood vessels. The objective of this study was to analyze the types and prevalence of comorbidities in patients with indications for carotid artery revascularization, as well as early results of endovascular carotid artery revascularization in relation to periprocedural complications. Material and Methods. This retrospective study was conducted from October 2014 to October 2019 and included 96 patients. Descriptive and comparative statistical analysis was performed in all patients, male and female, and those with both symptomatic and asymptomatic carotid diseases. Results. The study included 96 patients, of whom 69.8% were male and 30.2% were female. A successful endovascular procedure was performed in 89.6% of patients, while in 10.4% of patients the procedure failed. The distribution of patients by sex, age and the duration of procedure, showed a statistically significant difference (p &lt; 0.05) in the age (p = 0.0003) and duration of the procedure (p = 0.022). The comparison of two groups of patients, with symptomatic and asymptomatic carotid atherosclerotic disease, hyperlipoproteinemia (p = 0.015) showed a statistically significant difference (p &lt; 0.05) between the two groups. Conclusion. Endovascular revascularization has a high success rate in the treatment of atherosclerotic disease of the carotid arteries as well as low periprocedural morbidity and mortality. The analysis of gender-related differences, we concluded that endovascular revascularization lasts significantly longer in female patients, and that the average age is significantly higher in male patients compared to females. We also concluded that hyperlipoproteinemia is a major risk factor for carotid artery disease. Key words: Carotid Stenosis; Stroke; Cerebral Revascularization; Endovascular Procedures; Treatment Outcome; Stents; Atherosclerosis; Minimally Invasive Surgical Procedures: Risk Factors; Comorbidity Uvod. Endovaskularna revaskularizacija podrazumeva rekonstrukciju obolelog krvnog suda metodama koje se koriste da poboljsaju protok krvi kroz krvni sud. Cilj rada bila je analiza komorbiditeta po tipu i ucestalosti javljanja kod pacijenata sa indikacijom za revaskularizaciju karotidnih arterija, kao i analiza ranih rezultata endovaskularne revaskularizacije karotidnih arterija u odnosu na periproceduralne komplikacije. Materijal i metode. Retrospektivna studija izmedu oktobra 2014. i oktobra 2019. godine obuhvatila je 96 pacijenata. Radena je deskriptivna i komparativna statistika za celu populaciju izmedu grupe muskog i zenskog pola i simptomatske i asimptomatske karotidne bolesti. Rezultati. Istrazivanjem je obuhvaceno 96 bolesnika, od kojih je 69,8% bilo muskog, dok je 30,2% bilo zenskog pola. Uspesno izvrsena endovaskularna procedura je uradena kod 89,6% bolesnika, dok kod 10,4% bolesnika procedura nije uspela. Poredenjem pacijenata po polu, starosti (p = 0,0003) i trajanja procedure (p = 0,022) pokazala se statisticki znacajna razlika (p &lt; 0,05). Poredenjem dve grupe pacijenata sa simptomatskom i asimptomatskom karotidnom aterosklertoskom bolescu, hiperlipoproteinemija, (p = 0,015) pokazala se takode statisticki znacajna razlika (p &lt; 0,05). Zakljucak. Endovaskularnom revaskularizacijom se postize visok uspeh lecenja aterosklerotske bolesti karotidnih arterija, pracena je malim periproceduralnim morbiditetom i mortalitetom. Analizom rezultata po polu, zakljucili smo da endovaskularna revaskularizacija znacajno duze traje kod pacijenata zenskog pola i daje prosecna starost znacajno veca kod pacijenata muskog pola u odnosu na zenski pol. Zakljucili smo i da hiperlipoproteinemija ima znacajnu ulogu u simptomatologiji karotidne bolesti, kao i daje hiperlipoproteinemija znacajan faktor rizika za bolest karotidne arterije. Kljucne reci: karotidna stenoza; mozdani udar; cerebralna revaskularizacija; endovaskularne procedure; ishod lecenja; stentovi; ateroskleroza; minimalno invazivne hirurske procedure; faktori rizika; komorbiditet</abstract><pub>Drustvo Lekara Vojvodine</pub><doi>10.2298/MPNS2012351B</doi></addata></record>
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subjects Atherosclerosis
Comorbidity
Comparative analysis
Health aspects
Medical research
Medicine, Experimental
Mortality
Risk factors
Stenosis
Stroke (Disease)
title ENDOVASCULAR REVASCULARIZATION OF CAROTID ARTERY STENOSIS /ENDOVASKULARNA REVASKULARIZACIJA SUZENJA KAROTIDNE ARTERIJE
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