Muscle atrophy induced by overexpression of ALAS2 is related to muscle mitochondrial dysfunction

Background ALAS2 (delta-aminolevulinate synthase 2) is one of the two isoenzymes catalyzing the synthesis of delta-aminolevulinic acid (ALA), which is the first precursor of heme synthesis. ALAS2-overexpressing transgenic mice (Tg mice) showed syndrome of porphyria, a series of diseases related to t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Skeletal muscle 2021-03, Vol.11 (1), p.9-9, Article 9
Hauptverfasser:	Peng, Yahui, Li, Jihong, Luo, Dixian, Zhang, Shuai, Li, Sijia, Wang, Dayong, Wang, Xidi, Zhang, Zhujun, Wang, Xue, Sun, Changhui, Gao, Xu, Hui, Yang, He, Rongzhang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphate Alcohol Aminolevulinic acid Analysis Animals Antibodies ATP Atrophy Biosynthesis Cell Biology Cytoplasm Dehydrogenases Delta-aminolevulinate synthase 2 Deoxyribonucleic acid DNA Dystrophin Dystrophy Gene expression Genetic engineering Heme Immunohistochemistry Isoenzymes Life Sciences & Biomedicine Major histocompatibility complex Mice Mice, Transgenic Mitochondria Mitochondria, Muscle Mitochondrial DNA Mitochondrial dysfunction Muscle atrophy Muscle contraction Muscle Fibers, Skeletal - metabolism Muscle, Skeletal - metabolism Muscles Muscular Atrophy - metabolism Organelles Porphyria Protein biosynthesis Protein synthesis Proteins Proteolysis Quadriceps muscle RNA Science & Technology Skeletal muscle Transgenic animals Transgenic mice Transmission electron microscopes Utrophin
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!