Bile salt-dependent lipase promotes the barrier integrity of Caco-2 cells by activating Wnt/[beta]-catenin signaling via LRP6 receptor

Bile salt-dependent lipase (BSDL) within intestinal lumen can be endocytosed by enterocytes and support the intestinal barrier function. However, the epithelial-supporting effect of this protein has not been verified in a human cell line and neither the direct signaling pathway nor the function of e...

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Veröffentlicht in:Cell and tissue research 2021-03, Vol.383 (3), p.1077
Hauptverfasser: Qiu, Yaqi, Zhou, Jiefei, Zhang, Dandan, Song, Huanlei, Qian, Linxi
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Sprache:eng
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