Extracellular signal-regulated kinase 1/2 is required for complement component C1q and fibronectin dependent enhancement of Fc[gamma]- receptor mediated phagocytosis in mouse and human cells

C1q is a soluble pattern recognition protein that regulates multiple leukocyte functions, and deficiency in C1q results in autoimmunity. C1q stimulates enhanced phagocytic function through multiple mechanisms including the rapid enhancement of Fc[gamma] receptor (Fc[gamma]R) -mediated phagocytosis....

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Veröffentlicht in:	BMC immunology 2020-12, Vol.21 (1)
Hauptverfasser:	Willmann, Emily A, Pandurovic, Vesna, Jokinen, Anna, Beckley, Danielle, Bohlson, Suzanne S
Format:	Artikel
Sprache:	eng
Schlagworte:	Extracellular signal-regulated kinases Fibronectins Health aspects Phagocytosis Physiological aspects
Online-Zugang:	Volltext
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