Tissue-resident [PSGL1.sup.lo][CD4.sup.+] T cells promote B cell differentiation and chronic graft-versus-host disease-associated autoimmunity

[CD4.sup.+] T cell interactions with B cells play a critical role in the pathogenesis of systemic autoimmune diseases such as systemic lupus and chronic graft-versus-host disease (cGVHD). Extrafollicular [CD44.sup.hi][CD62L.sup.lo][PSGL1.sup.lo][CD4.sup.+] T cells ([PSGL1.sup.lo][CD4.sup.+] T cells)...

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Veröffentlicht in:	The Journal of clinical investigation 2021-01, Vol.131 (1)
Hauptverfasser:	Kong, Xiaohui, Zeng, Deye, Wu, Xiwei, Wang, Bixin, Yang, Shijie, Song, Qingxiao, Zhu, Yongping, Salas, Martha, Qin, Hanjun, Nasri, Ubaydah, Haas, Karen M, Riggs, Arthur D, Nakamura, Ryotaro, Martin, Paul J, Huang, Aimin, Zeng, Defu
Format:	Artikel
Sprache:	eng
Schlagworte:	B cells CD4 lymphocytes Development and progression Graft versus host reaction Health aspects Physiological aspects
Online-Zugang:	Volltext
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