Neuroprotective Effect of Antioxidants in the Brain

The brain is vulnerable to excessive oxidative insults because of its abundant lipid content, high energy requirements, and weak antioxidant capacity. Reactive oxygen species (ROS) increase susceptibility to neuronal damage and functional deficits, via oxidative changes in the brain in neurodegenera...

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Veröffentlicht in:	International journal of molecular sciences 2020-10, Vol.21 (19), p.7152, Article 7152
Hauptverfasser:	Lee, Kyung Hee, Cha, Myeounghoon, Lee, Bae Hwan
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Animals antioxidant Antioxidants Antioxidants - therapeutic use Apoptosis Biochemistry & Molecular Biology Brain Brain - drug effects Brain - metabolism Brain - pathology Brain damage Brain injury Cell death Cell Death - drug effects Cell Death - genetics Chemistry Chemistry, Multidisciplinary Clinical trials Clinical Trials as Topic DNA Damage Energy requirements Enzymes Fatty acids Free radicals Gene expression Health aspects Homeostasis Humans Intracellular signalling Life Sciences & Biomedicine Lipid peroxidation Lipid Peroxidation - drug effects Lipids Metabolism Metabolites Metals Mitochondria Neural circuitry Neurodegeneration neurodegenerative disease Neurodegenerative Diseases - drug therapy Neurodegenerative Diseases - genetics Neurodegenerative Diseases - metabolism Neurodegenerative Diseases - pathology Neurons - drug effects Neurons - metabolism Neurons - pathology Neuroprotection Neuroprotective Agents - therapeutic use Oxidation Oxidation-Reduction Oxidative Stress Physical Sciences Propagation Proteins Reactive Oxygen Species - antagonists & inhibitors Reactive Oxygen Species - metabolism Review Science & Technology Signal Transduction Superoxide Dismutase - metabolism Vitamin E Vitamins - metabolism Zinc
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