Retinoic Acid Sensitivity of Triple-Negative Breast Cancer Cells Characterized by Constitutive Activation of the notch1 Pathway: The Role of Rar[beta]

We provide experimental evidence that the rare subgroup of triple-negative breast cancer characterized by constitutive activation of the NOTCH1 signaling pathway is sensitive to the anti-tumor action of all-trans retinoic acid, the active metabolite of vitamin A. In this tumor context, all-trans ret...

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Veröffentlicht in:	Cancers 2020-10, Vol.12 (10), p.1
Hauptverfasser:	Paroni, Gabriela, Zanetti, Adriana, Barzago, Maria Monica, Kurosaki, Mami, Guarrera, Luca, Fratelli, Maddalena, Troiani, Martina, Ubezio, Paolo, Vallerga, Bolis Arianna, Biancardi, Federica, Terao, Mineko, Garattini, Enrico
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Cancer cells Health aspects Physiological aspects Tretinoin
Online-Zugang:	Volltext
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