Evaluation of therapeutic targeting of CCR7 in acute graft-versus-host disease

Graft-versus-host disease (GVHD) is the main complication after allogeneic hematopoietic stem cell transplantation. We previously unveiled a correlation between proportions of C-C motif chemokine receptor 7 (CCR7) + T cells in the apheresis and the risk of developing GVHD. We wanted to evaluate in v...

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Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 2020-10, Vol.55 (10), p.1935-1945
Hauptverfasser:	Cuesta-Mateos, Carlos, Portero-Sainz, Itxaso, García-Peydró, Marina, Alcain, Juan, Fuentes, Patricia, Juárez-Sánchez, Raquel, Pérez-García, Yaiza, Mateu-Albero, Tamara, Díaz-Fernández, Paula, Vega-Piris, Lorena, Sánchez-López, Blanca A., Marcos-Jiménez, Ana, Cardeñoso, Laura, Gómez-García de Soria, Valle, Toribio, María Luisa, Muñoz-Calleja, Cecilia
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/2 13/31 631/250/1904 631/250/98 631/532/1542 64/60 692/699/1541/1990 692/699/249/1529 96/21 Antibodies Apheresis Biophysics CC chemokine receptors CCR7 protein CD45RA antigen Cell Biology Complement activation Cytomegalovirus Cytomegalovirus infections Diseases Effector cells Graft versus host disease Graft-versus-host reaction Grafting Health aspects Health services Hematology Hematopoietic stem cells Immunological memory Immunology Internal Medicine Leukemia Life Sciences & Biomedicine Life span Lymphocytes Lymphocytes T Medical research Medicine Medicine & Public Health Medicine, Experimental Memory cells Monoclonal antibodies Oncology Public Health Relapse Science & Technology Stem cell transplantation Stem Cells T cells Therapeutic targets Transplantation
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