Human granulocyte-colony stimulating factor fusion proteins: design, characterization and activity

Background Stem cell factor (SCF) and granulocyte-colony stimulating factor (G-CSF) are well-characterized vital hematopoietic growth factors that regulate hematopoiesis. G-CSF and SCF synergistically exhibit a stimulatory effect on hematopoietic progenitors. The combination of G-CSF and SCF has bee...

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Veröffentlicht in:	PeerJ (San Francisco, CA) CA), 2020-08, Vol.8, p.e9788
Hauptverfasser:	Mickiene, Gitana, DalgÄdienÄ, IndrÄ, Zvirblis, Gintautas, Dapkunas, Zilvinas, Plikusiene, Ieva, Buzavaite-Verteliene, Ernesta, Balevicius, Zigmas, RuksÄnaitÄ, AudronÄ, Pleckaityte, Milda
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Cytokines Hematopoietic stem cell transplantation High performance liquid chromatography Mass spectrometry Pegfilgrastim Protein binding Recombinant proteins Stem cells
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