Particle characterization and toxicity in C57BL/6 mice following instillation of five different diesel exhaust particles designed to differ in physicochemical properties

Background Diesel exhaust is carcinogenic and exposure to diesel particles cause health effects. We investigated the toxicity of diesel exhaust particles designed to have varying physicochemical properties in order to attribute health effects to specific particle characteristics. Particles from thre...

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Veröffentlicht in:	Particle and fibre toxicology 2020-08, Vol.17 (1), p.1-25, Article 38
Hauptverfasser:	Bendtsen, Katja Maria, Gren, Louise, Malmborg, Vilhelm Berg, Shukla, Pravesh Chandra, Tuner, Martin, Essig, Yona J., Krais, Annette M., Clausen, Per Axel, Berthing, Trine, Loeschner, Katrin, Jacobsen, Nicklas Raun, Wolff, Henrik, Pagels, Joakim, Vogel, Ulla Birgitte
Format:	Artikel
Sprache:	eng
Schlagworte:	Arbetsmedicin och miljömedicin Aromatic hydrocarbons Black carbon Carbon Carbon black Carbon content Carcinogens Chemical composition Chemical properties Deoxyribonucleic acid Diesel emissions Diesel engines Diesel exhaust particles - ultrafine particles Diesel fuels DNA DNA damage Engine inlets Environmental Health and Occupational Health Exhaust gas recirculation Exposure Gases Genotoxicity Health aspects Health Sciences Hälsovetenskap Inflammation Intratracheal instillation Life Sciences & Biomedicine Liver Lungs Mass spectrometry Medical and Health Sciences Medicin och hälsovetenskap Metals Morphology Organic carbon Particle size Particulate pollutants Particulates Physical properties Physicochemical properties Polycyclic aromatic hydrocarbons Rapeseed Renewable diesel fuels Retention Risk factors Science & Technology Scientific imaging Specific surface Sulfur Surface area Testing Toxicity Toxicology Trachea Transmission electron microscopy Vegetable oils
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