Subcutaneous Immunization of Leishmania HSP70-II Null Mutant Line Reduces the Severity of the Experimental Visceral Leishmaniasis in BALB/c Mice

Leishmania infantum parasites cause a severe form of visceral leishmaniasis in human and viscerocutaneous leishmaniasis in dogs. Recently, we reported that immunization with an attenuated L. infantum cell line, lacking the hsp70-II gene, protects against the development of murine cutaneous leishmani...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Vaccines (Basel) 2020-03, Vol.8 (1), p.141, Article 141
Hauptverfasser:	Carlos Solana, Jose, Ramirez, Laura, Cook, Emma C. L., Hernandez-Garcia, Elena, Sacristan, Silvia, Elena Martin, M., Manuel Gonzalez, Victor, Maria Reguera, Rosa, Balana-Fouce, Rafael, Fresno, Manuel, Maria Requena, Jose, Iborra, Salvador, Soto, Manuel
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal diseases Animals attenuated parasites Biotechnology Bone marrow CD4 antigen CD8 antigen Cutaneous leishmaniasis Damage detection Dilution Gene mutation Genetic aspects Health aspects Hsp70 protein ifn-γ Immune response Immune system Immunization Immunology In vivo methods and tests Infections Life Sciences & Biomedicine Liver Lymphatic system Lymphocytes Lymphocytes T Medical imaging Medicine, Research & Experimental mice Mutants Parasites Parasitic diseases Penicillin Research & Experimental Medicine Science & Technology Spleen t-cells vaccine Vaccines Vector-borne diseases Visceral leishmaniasis γ-Interferon
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!